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- Title
Aortic Stiffness, Blood Pressure Progression, and Incident Hypertension.
- Authors
Kaess, Bernhard M.; Jian Rong; Larson, Martin G.; Hamburg, Naomi M.; Vita, Joseph A.; Levy, Daniel; Benjamin, Emelia J.; Vasan, Ramachandran S.; Mitchell, Gary F.
- Abstract
The article presents information on vascular stiffness that increases as the age of the person increases and is the major cause of the age related morbidity and mortality. It informs that the stiffening of the aortic wall is associated with elevated pulse wave velocity (PWV) and prematurewave reflection that results in the increase in the pulsatile hemodynamic load, cardiac after load and reduces diastolic coronary flowing high flow organs such as the kidneys and brain. It further informs that the European Society of Cardiology considers elevated PWV a negative prognostic factor to be considered in the management of patients with hypertension
- Subjects
ARTERIAL diseases; AGE; AORTA; DISEASES; MORTALITY; HEMODYNAMICS; DIASTOLE (Cardiac cycle); PATIENTS; HYPERTENSION
- Publication
JAMA: Journal of the American Medical Association, 2012, Vol 308, Issue 9, p875
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/2012.jama.10503