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- Title
Recognition of Risk for Clinically Significant Drug Interactions among HIV-Infected Patients Receiving Antiretroviral Therapy.
- Authors
Evans-Jones, John G.; Cottle, Lucy E.; Back, David J.; Gibbons, Sara; Beeching, Nicholas J.; Carey, Peter B.; Khoo, Saye H.
- Abstract
We assessed the risk of clinically significant drug interactions in patients receiving antiretrovirals, and their recognition by physicians. Clinically significant drug interactions were recorded in 27% of 159 patients, with 15% of interactions potentially lowering antiretroviral concentrations. Risk of clinically significant drug interactions was significantly related to receipt of protease inhibitors. Only 36% of clinically significant drug interactions were correctly identified by physicians.
- Subjects
DRUG interactions; DRUG side effects; ANTIRETROVIRAL agents; PROTEASE inhibitors; ENZYME inhibitors; DRUG antagonism
- Publication
Clinical Infectious Diseases, 2010, Vol 50, Issue 10, p1419
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1086/652149