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Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs.
Published in:
Angewandte Chemie, 2018, v. 130, n. 41, p. 13770, doi. 10.1002/ange.201809056
By:
- Fenton, Owen S.;
- Kauffman, Kevin J.;
- McClellan, Rebecca L.;
- Kaczmarek, James C.;
- Zeng, Manhao D.;
- Andresen, Jason L.;
- Rhym, Luke H.;
- Heartlein, Michael W.;
- DeRosa, Frank;
- Anderson, Daniel G.
Publication type:
Article
Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs.
Published in:
Angewandte Chemie, 2016, v. 128, n. 44, p. 14012, doi. 10.1002/ange.201608450
By:
- Kaczmarek, James C.;
- Patel, Asha K.;
- Kauffman, Kevin J.;
- Fenton, Owen S.;
- Webber, Matthew J.;
- Heartlein, Michael W.;
- DeRosa, Frank;
- Anderson, Daniel G.
Publication type:
Article
Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs.
Published in:
Angewandte Chemie International Edition, 2018, v. 57, n. 41, p. 13582, doi. 10.1002/anie.201809056
By:
- Fenton, Owen S.;
- Kauffman, Kevin J.;
- McClellan, Rebecca L.;
- Kaczmarek, James C.;
- Zeng, Manhao D.;
- Andresen, Jason L.;
- Rhym, Luke H.;
- Heartlein, Michael W.;
- DeRosa, Frank;
- Anderson, Daniel G.
Publication type:
Article
Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs.
Published in:
Angewandte Chemie International Edition, 2016, v. 55, n. 44, p. 13808, doi. 10.1002/anie.201608450
By:
- Kaczmarek, James C.;
- Patel, Asha K.;
- Kauffman, Kevin J.;
- Fenton, Owen S.;
- Webber, Matthew J.;
- Heartlein, Michael W.;
- DeRosa, Frank;
- Anderson, Daniel G.
Publication type:
Article
Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases.
Published in:
BMC Immunology, 2010, v. 11, p. 43, doi. 10.1186/1471-2172-11-43
By:
- Martini, Paolo G. V.;
- Cook, Lynette C.;
- Alderucci, Scott;
- Norton, Angela W.;
- Lundberg, Dianna M.;
- Fish, Susan M.;
- Langsetmo, Knut;
- Jönsson, Göran;
- Lood, Christian;
- Gullstrand, Birgitta;
- Zaleski, Kate J.;
- Savioli, Nancy;
- Lottherand, Jason;
- Bedard, Charles;
- Gill, John;
- Concino, Michael F.;
- Heartlein, Michael W.;
- Truedsson, Lennart;
- Powell, Jan L.;
- Tzianabos, Arthur O.
Publication type:
Article
CNS Penetration of Intrathecal-Lumbar Idursulfase in the Monkey, Dog and Mouse: Implications for Neurological Outcomes of Lysosomal Storage Disorder.
Published in:
PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030341
By:
- Calias, Pericles;
- Papisov, Mikhail;
- Jing Pan;
- Savioli, Nancy;
- Belov, Vasily;
- Yan Huang;
- Lotterhand, Jason;
- Alessandrini, Mary;
- Nan Liu;
- Fischman, Alan J.;
- Powell, Jan L.;
- Michael W. Heartlein
Publication type:
Article
Gene Delivery: Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium (Adv. Mater. 8/2019).
Published in:
Advanced Materials, 2019, v. 31, n. 8, p. N.PAG, doi. 10.1002/adma.201970053
By:
- Patel, Asha Kumari;
- Kaczmarek, James C.;
- Bose, Suman;
- Kauffman, Kevin J.;
- Mir, Faryal;
- Heartlein, Michael W.;
- DeRosa, Frank;
- Langer, Robert;
- Anderson, Daniel G.
Publication type:
Article
Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium.
Published in:
Advanced Materials, 2019, v. 31, n. 8, p. N.PAG, doi. 10.1002/adma.201805116
By:
- Patel, Asha Kumari;
- Kaczmarek, James C.;
- Bose, Suman;
- Kauffman, Kevin J.;
- Mir, Faryal;
- Heartlein, Michael W.;
- DeRosa, Frank;
- Langer, Robert;
- Anderson, Daniel G.
Publication type:
Article
Synthesis and Biological Evaluation of Ionizable Lipid Materials for the In Vivo Delivery of Messenger RNA to B Lymphocytes.
Published in:
Advanced Materials, 2017, v. 29, n. 33, p. n/a, doi. 10.1002/adma.201606944
By:
- Fenton, Owen S.;
- Kauffman, Kevin J.;
- Kaczmarek, James C.;
- McClellan, Rebecca L.;
- Jhunjhunwala, Siddharth;
- Tibbitt, Mark W.;
- Zeng, Manhao D.;
- Appel, Eric A.;
- Dorkin, Joseph R.;
- Mir, Faryal F.;
- Yang, Jung H.;
- Oberli, Matthias A.;
- Heartlein, Michael W.;
- DeRosa, Frank;
- Langer, Robert;
- Anderson, Daniel G.
Publication type:
Article
Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery.
Published in:
Advanced Materials, 2016, v. 28, n. 15, p. 2939, doi. 10.1002/adma.201505822
By:
- Fenton, Owen S.;
- Kauffman, Kevin J.;
- McClellan, Rebecca L.;
- Appel, Eric A.;
- Dorkin, J. Robert;
- Tibbitt, Mark W.;
- Heartlein, Michael W.;
- DeRosa, Frank;
- Langer, Robert;
- Anderson, Daniel G.
Publication type:
Article
Safety Evaluation of Chronic Intrathecal Administration of Idursulfase-IT in Cynomolgus Monkeys.
Published in:
Toxicologic Pathology, 2011, v. 39, n. 5, p. 879, doi. 10.1177/0192623311409595
By:
- Felice, Brian R.;
- Wright, Teresa L.;
- Boyd, Robert B.;
- Butt, Mark T.;
- Pfeifer, Richard W.;
- Pan, Jing;
- Ruiz, Juan A.;
- Heartlein, Michael W.;
- Calias, Pericles
Publication type:
Article
Human Sulfatase 2 inhibits in vivo tumor growthof MDA-MB-231 human breast cancer xenografts.
Published in:
BMC Cancer, 2010, v. 10, p. 427, doi. 10.1186/1471-2407-10-427
By:
- Peterson, Sarah M.;
- Iskenderian, Andrea;
- Cook, Lynette;
- Romashko, Alla;
- Tobin, Kristen;
- Jones, Michael;
- Norton, Angela;
- Gómez-Yafal, Alicia;
- Heartlein, Michael W.;
- Concino, Michael F.;
- Liaw, Lucy;
- Martini, Paolo G. V.
Publication type:
Article

Found: 12