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Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 8, p. 3634, doi. 10.1172/JCI69866
By:
- Nayumi Shigihara;
- Ayako Fukunaka;
- Akemi Hara;
- Koji Komiya;
- Akira Honda;
- Toyoyoshi Uchida;
- Hiroko Abe;
- Yukiko Toyofuku;
- Motoyuki Tamaki;
- Takeshi Ogihara;
- Takeshi Miyatsuka;
- Hiddinga, Henry J.;
- Setsuya Sakagashira;
- Masato Koike;
- Yasuo Uchiyama;
- Tamotsu Yoshimori;
- Eberhardt, Norman L.;
- Yoshio Fujitani;
- Hirotaka Watada
Publication type:
Article
The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 10, p. 4513, doi. 10.1172/JCI68807
By:
- Motoyuki Tamaki;
- Yoshio Fujitani;
- Akemi Hara;
- Toyoyoshi Uchida;
- Yoshifumi Tamura;
- Kageumi Takeno;
- Minako Kawaguchi;
- Takahiro Watanabe;
- Takeshi Ogihara;
- Ayako Fukunaka;
- Tomoaki Shimizu;
- Tomoya Mita;
- Akio Kanazawa;
- Mica O. Imaizumi;
- Takaya Abe;
- Hiroshi Kiyonari;
- Shintaro Hojyo;
- Toshiyuki Fukada;
- Takeshi Kawauchi;
- Shinya Nagamatsu
Publication type:
Article
Serotonin regulates pancreatic beta cell mass during pregnancy.
Published in:
Nature Medicine, 2010, v. 16, n. 7, p. 804, doi. 10.1038/nm.2173
By:
- Hail Kim;
- Toyofuku, Yukiko;
- Lynn, Francis C;
- Chak, Eric;
- Uchida, Toyoyoshi;
- Mizukami, Hiroki;
- Fujitani, Yoshio;
- Kawamori, Ryuzo;
- Miyatsuka, Takeshi;
- Kosaka, Yasuhiro;
- Yang, Katherine;
- Honig, Gerard;
- van der Hart, Marieke;
- Kishimoto, Nina;
- Wang, Juehu;
- Yagihashi, Soroku;
- Tecott, Laurence H;
- Watada, Hirotaka;
- German, Michael S.
Publication type:
Article
Effect of Plasma Exchange in Thyroid Storm With Consideration of Its Distribution Into the Extravascular Space.
Published in:
Journal of the Endocrine Society, 2020, v. 4, n. 4, p. N.PAG, doi. 10.1210/jendso/bvaa023
By:
- Shinohara, Mai;
- Uchida, Toyoyoshi;
- Funayama, Takashi;
- Watanabe, Mika;
- Kusaoi, Makio;
- Yamaji, Ken;
- Tamura, Naoto;
- Goto, Hiromasa;
- Sato, Hiroaki;
- Watada, Hirotaka
Publication type:
Article
The Effect of Long-Term Inorganic Iodine on Intrathyroidal Iodothyronine Content and Gene Expression in Mice with Graves' Hyperthyroidism.
Published in:
Thyroid, 2023, v. 33, n. 3, p. 330, doi. 10.1089/thy.2022.0496
By:
- Uchida, Toyoyoshi;
- Shimamura, Mika;
- Taka, Hikari;
- Kaga, Naoko;
- Miura, Yoshiki;
- Nishida, Yuya;
- Nagayama, Yuji;
- Watada, Hirotaka
Publication type:
Article
Influence of Short-Term Dietary and Therapeutic Iodine Restriction on the Therapeutic Effects of Radioactive Iodine Therapy in Patients with Graves' Disease.
Published in:
Thyroid, 2021, v. 31, n. 3, p. 439, doi. 10.1089/thy.2020.0126
By:
- Nishio, Rie;
- Uchida, Toyoyoshi;
- Suzuki, Luka;
- Onose, Hiroyuki;
- Goto, Hiromasa;
- Yamada, Emiko;
- Satoh, Hiroaki;
- Watada, Hirotaka
Publication type:
Article
High prevalence of anti- TSH receptor antibody in fibromyalgia syndrome.
Published in:
International Journal of Rheumatic Diseases, 2017, v. 20, n. 6, p. 685, doi. 10.1111/1756-185X.12964
By:
- Nishioka, Kenya;
- Uchida, Toyoyoshi;
- Usui, Chie;
- Tanaka, Ryota;
- Matsushima, Takashi;
- Matsumoto, Yoshifuji;
- Nakamura, Ikuro;
- Nishioka, Kusuki;
- Hattori, Nobutaka
Publication type:
Article
Effect of treatment guidance using a retrospective continuous glucose monitoring system on glycaemic control in outpatients with type 2 diabetes mellitus: A randomized controlled trial*.
Published in:
Journal of International Medical Research, 2016, v. 44, n. 1, p. 109, doi. 10.1177/0300060515600190
By:
- Sato, Junko;
- Kanazawa, Akio;
- Ikeda, Fuki;
- Shigihara, Nayumi;
- Kawaguchi, Minako;
- Komiya, Koji;
- Uchida, Toyoyoshi;
- Ogihara, Takeshi;
- Mita, Tomoya;
- Shimizu, Tomoaki;
- Fujitani, Yoshio;
- Watada, Hirotaka
Publication type:
Article
Novel approaches to the management of recurrent pregnancy loss: The OPTIMUM (OPtimization of Thyroid function, Thrombophilia, Immunity, and Uterine Milieu) treatment strategy.
Published in:
Reproductive Medicine & Biology, 2021, v. 20, n. 4, p. 524, doi. 10.1002/rmb2.12412
By:
- Kuroda, Keiji;
- Ikemoto, Yuko;
- Horikawa, Takashi;
- Moriyama, Azusa;
- Ojiro, Yuko;
- Takamizawa, Satoru;
- Uchida, Toyoyoshi;
- Nojiri, Shuko;
- Nakagawa, Koji;
- Sugiyama, Rikikazu
Publication type:
Article
Pseudohyperkalemia in myotonic dystrophy type 1: A case report.
Published in:
2024
By:
- Hatano, Taku;
- Uchida, Toyoyoshi;
- Hayashi, Hidemori;
- Hattori, Nobutaka
Publication type:
Case Study
2-Methoxyestradiol ameliorates glucose tolerance with the increase in β-cell mass in db/ db mice.
Published in:
Journal of Diabetes Investigation, 2011, v. 2, n. 3, p. 180, doi. 10.1111/j.2040-1124.2010.00087.x
By:
- Yorifuji, Takashi;
- Uchida, Toyoyoshi;
- Abe, Hiroko;
- Toyofuku, Yukiko;
- Tamaki, Motoyuki;
- Fujitani, Yoshio;
- Hirose, Takahisa;
- Kawamori, Ryuzo;
- Takeda, Satoru;
- Watada, Hirotaka
Publication type:
Article
Combination treatment of db/db mice with exendin-4 and gastrin preserves β-cell mass by stimulating β-cell growth and differentiation.
Published in:
Journal of Diabetes Investigation, 2010, v. 1, n. 5, p. 172, doi. 10.1111/j.2040-1124.2010.00044.x
By:
- Tamaki, Motoyuki;
- Fujitani, Yoshio;
- Uchida, Toyoyoshi;
- Hirose, Takahisa;
- Kawamori, Ryuzo;
- Watada, Hirotaka
Publication type:
Article
Impact of oxidative stress and peroxisome proliferator-activated receptor gamma coactivator-1alpha in hepatic insulin resistance.
Published in:
2008
By:
- Kumashiro N;
- Tamura Y;
- Uchida T;
- Ogihara T;
- Fujitani Y;
- Hirose T;
- Mochizuki H;
- Kawamori R;
- Watada H;
- Kumashiro, Naoki;
- Tamura, Yoshifumi;
- Uchida, Toyoyoshi;
- Ogihara, Takeshi;
- Fujitani, Yoshio;
- Hirose, Takahisa;
- Mochizuki, Hideki;
- Kawamori, Ryuzo;
- Watada, Hirotaka
Publication type:
journal article
Impact of Oxidative Stress and Peroxisome Proliferator-Activated Receptor γ Coactivator-1α in Hepatic Insulin Resistance.
Published in:
Diabetes, 2008, v. 57, n. 8, p. 2083, doi. 10.2337/db08-0144
By:
- Kumashiro, Naoki;
- Tamura, Yoshifumi;
- Uchida, Toyoyoshi;
- Ogihara, Takeshi;
- Fujitani, Yoshio;
- Hirose, Takahisa;
- Mochizuki, Hideki;
- Kawamori, Ryuzo;
- Watada, Hirotaka
Publication type:
Article
Effect of Hedgehog Signal Intensity on Pancreas Morphogenesis.
Published in:
Diabetes, 2007, v. 56, p. A416
By:
- Nakayama, Shiho;
- Watada, Hirotaka;
- Fujitani, Yoshio;
- Igarashi, Yasuhiro;
- Iwashita, Noseki;
- Ikeda, Fuki;
- Kanno, Rei;
- Uchida, Toyoyoshi;
- Ogihara, Takeshi;
- Motoyama, Jun;
- Kawamori, Ryuzo
Publication type:
Article
Comparison of the therapeutic effects of prednisolone and nonsteroidal anti-inflammatory drugs in patients with subacute thyroiditis.
Published in:
Endocrine (1355008X), 2017, v. 55, n. 1, p. 209, doi. 10.1007/s12020-016-1122-3
By:
- Sato, Junko;
- Uchida, Toyoyoshi;
- Komiya, Koji;
- Goto, Hiromasa;
- Takeno, Kageumi;
- Suzuki, Ruriko;
- Honda, Akira;
- Himuro, Miwa;
- Watada, Hirotaka
Publication type:
Article
Therapeutic effectiveness of potassium iodine in drug-naïve patients with Graves' disease: a single-center experience.
Published in:
Endocrine (1355008X), 2014, v. 47, n. 2, p. 506, doi. 10.1007/s12020-014-0171-8
By:
- Uchida, Toyoyoshi;
- Goto, Hiromasa;
- Kasai, Takatoshi;
- Komiya, Koji;
- Takeno, Kageumi;
- Abe, Hiroko;
- Shigihara, Nayumi;
- Sato, Junko;
- Honda, Akira;
- Mita, Tomoya;
- Kanazawa, Akio;
- Fujitani, Yoshio;
- Watada, Hirotaka
Publication type:
Article
Elevated serum thyroid-stimulating hormone is associated with decreased anti-Müllerian hormone in infertile women of reproductive age.
Published in:
Journal of Assisted Reproduction & Genetics, 2015, v. 32, n. 2, p. 243, doi. 10.1007/s10815-014-0397-7
By:
- Kuroda, Keiji;
- Uchida, Toyoyoshi;
- Nagai, Saki;
- Ozaki, Rie;
- Yamaguchi, Takashi;
- Sato, Yuichi;
- Brosens, Jan;
- Takeda, Satoru
Publication type:
Article
Analysis of the risk factors and treatment for repeated implantation failure: OPtimization of Thyroid function, IMmunity, and Uterine Milieu (OPTIMUM) treatment strategy.
Published in:
American Journal of Reproductive Immunology, 2021, v. 85, n. 5, p. 1, doi. 10.1111/aji.13376
By:
- Kuroda, Keiji;
- Matsumura, Yuko;
- Ikemoto, Yuko;
- Segawa, Tomoya;
- Hashimoto, Tomoko;
- Fukuda, Junichiro;
- Nakagawa, Koji;
- Uchida, Toyoyoshi;
- Ochiai, Asako;
- Horimoto, Yoshiya;
- Arakawa, Atsushi;
- Nojiri, Shuko;
- Itakura, Atsuo;
- Sugiyama, Rikikazu
Publication type:
Article
GH-induced LH hyporesponsiveness as a potential mechanism for hypogonadism in male patients with acromegaly.
Published in:
Endocrine Journal, 2021, v. 68, n. 8, p. 953, doi. 10.1507/endocrj.ej20-0596
By:
- Rie Nishio;
- Akira Takeshita;
- Toyoyoshi Uchida;
- Takashi Herai;
- Kenichi Sakamoto;
- Yuichiro Shimizu;
- Makoto Arai;
- Keita Tatsushima;
- Noriaki Fukuhara;
- Mitsuo Okada;
- Hiroshi Nishioka;
- Shozo Yamada;
- Noriyuki Koibuchi;
- Hirotaka Watada;
- Yasuhiro Takeuchi
Publication type:
Article
Effect of thyroxine treatment on pregnancy outcomes in infertile Japanese women with TSH levels between 2.5 µIU/mL and the upper reference limit: a retrospective study.
Published in:
Endocrine Journal, 2021, v. 68, n. 2, p. 171, doi. 10.1507/endocrj.ej20-0380
By:
- Asako Tsunemi;
- Toyoyoshi Uchida;
- Keiji Kuroda;
- Yuko Ikemoto;
- Asako Ochiai;
- Hiromasa Goto;
- Rikikazu Sugiyama;
- Hiroaki Satoh;
- Atsuo Itakura;
- Hirotaka Watada
Publication type:
Article
Cutoff value of thyroid uptake of <sup>99m</sup>Tc-pertechnetate to discriminate between Graves' disease and painless thyroiditis: a single center retrospective study.
Published in:
Endocrine Journal, 2016, v. 63, n. 2, p. 143, doi. 10.1507/endocrj.ej15-0441
By:
- Toyoyoshi Uchida;
- Ruriko Suzuki;
- Takatoshi Kasai;
- Hiroyuki Onose;
- Koji Komiya;
- Hiromasa Goto;
- Kageumi Takeno;
- Shinya Ishii;
- Junko Sato;
- Akira Honda;
- Yui Kawano;
- Miwa Himuro;
- Emiko Yamada;
- Tetsu Yamada;
- Hirotaka Watada
Publication type:
Article
Switching from Twice-Daily Basal Insulin Injections to Once-Daily Insulin Degludec Injection for Basal-Bolus Insulin Regimen in Japanese Patients with Type 1 Diabetes: A Pilot Study.
Published in:
International Journal of Endocrinology, 2015, v. 2015, p. 1, doi. 10.1155/2015/176261
By:
- Tosaka, Yuka;
- Kanazawa, Akio;
- Ikeda, Fuki;
- Iida, Mayu;
- Sato, Junko;
- Matsumoto, Kazuhisa;
- Uchida, Toyoyoshi;
- Tamura, Yoshifumi;
- Ogihara, Takeshi;
- Mita, Tomoya;
- Shimizu, Tomoaki;
- Goto, Hiromasa;
- Ohmura, Chie;
- Fujitani, Yoshio;
- Watada, Hirotaka
Publication type:
Article
Prevalence of Amiodarone-Induced Thyrotoxicosis and Associated Risk Factors in Japanese Patients.
Published in:
International Journal of Endocrinology, 2014, p. 1, doi. 10.1155/2014/534904
By:
- Toyoyoshi Uchida;
- Takatoshi Kasai;
- Atsutoshi Takagi;
- Gaku Sekita;
- Koji Komiya;
- Kageumi Takeno;
- Nayumi Shigihara;
- Kazunori Shimada;
- Katsumi Miyauchi;
- Yoshio Fujitani;
- Hiroyuki Daida;
- Hirotaka Watada
Publication type:
Article
Arginine vasopressin deficiency onset after COVID-19 vaccination with positive anti-rabphilin-3A antibodies: a case report and literature review.
Published in:
BMC Endocrine Disorders, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12902-024-01664-8
By:
- Takizawa, Hiroki;
- Goto, Hiromasa;
- Uchida, Toyoyoshi;
- Aoyama, Shuhei;
- Fujisawa, Haruki;
- Iwata, Naoko;
- Suzuki, Atsushi;
- Sugimura, Yoshihisa;
- Watada, Hirotaka
Publication type:
Article
Disorganized Steroidogenesis in Adrenocortical Carcinoma, a Case Study.
Published in:
Endocrine Pathology, 2017, v. 28, n. 1, p. 27, doi. 10.1007/s12022-016-9441-8
By:
- Uchida, Toyoyoshi;
- Nishimoto, Koshiro;
- Fukumura, Yuki;
- Asahina, Miki;
- Goto, Hiromasa;
- Kawano, Yui;
- Shimizu, Fumitaka;
- Tsujimura, Akira;
- Seki, Tsugio;
- Mukai, Kuniaki;
- Kabe, Yasuaki;
- Suematsu, Makoto;
- Gomez-Sanchez, Celso;
- Yao, Takashi;
- Horie, Shigeo;
- Watada, Hirotaka
Publication type:
Article
One year follow-up after a randomized controlled trial of a 130 g/day low-carbohydrate diet in patients with type 2 diabetes mellitus and poor glycemic control.
Published in:
PLoS ONE, 2017, v. 12, n. 12, p. 1, doi. 10.1371/journal.pone.0188892
By:
- Sato, Junko;
- Kanazawa, Akio;
- Hatae, Chie;
- Makita, Sumiko;
- Komiya, Koji;
- Shimizu, Tomoaki;
- Ikeda, Fuki;
- Tamura, Yoshifumi;
- Ogihara, Takeshi;
- Mita, Tomoya;
- Goto, Hiromasa;
- Uchida, Toyoyoshi;
- Miyatsuka, Takeshi;
- Ohmura, Chie;
- Watanabe, Takehito;
- Kobayashi, Kiyoe;
- Miura, Yoshiko;
- Iwaoka, Manami;
- Hirashima, Nao;
- Watada, Hirotaka
Publication type:
Article
225-OR: The Impact of Visualizing Macronutrient Content via Food-Log App "Calomeal" on Glycemic Control and QoL in People with Type 2 Diabetes.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-225-OR
By:
- TSUNEMI, ASAKO;
- SATO, JUNKO;
- ENOMOTO, MARI;
- IWAGAKI, YUKO;
- SUGIMOTO, SAKAE;
- SOMEYA, YUKI;
- KIYA, MAI;
- MATSUHASHI, EIKO;
- WAKABAYASHI, YUKA;
- FUNAYAMA, TAKASHI;
- UCHIDA, TOYOYOSHI;
- MIYATSUKA, TAKESHI;
- AZUMA, KOSUKE;
- SHIMIZU, TOMOAKI;
- SATOH, HIROAKI;
- KANAZAWA, AKIO;
- WATADA, HIROTAKA
Publication type:
Article

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