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- Title
Molecular modelling of HLA-B*35:132.
- Authors
Longhi, E.; Crivello, P.; Mantovani, M.; Frison, S.; Fleischhauer, K.; Crespiatico, L.; Piccolo, G.; Poli, F.
- Abstract
Here we describe the molecular modelling of the new variant HLA- B*35:132. This allele shows one mismatch with B*35:01:01:01 in exon 3 at position 575 where a T is substituted by a C, which implies an amino acidic change from Leucine to Proline. This seems not to alter the molecular structure and not to compromise the HLA complex and T-cell receptor interaction.
- Subjects
HLA histocompatibility antigens; MOLECULAR models; HISTOCOMPATIBILITY antigens; T-cell receptor genes; LEUCINE; PROLINE; AMINO acids; BRANCHED chain amino acids
- Publication
International Journal of Immunogenetics, 2014, Vol 41, Issue 3, p195
- ISSN
1744-3121
- Publication type
Article
- DOI
10.1111/iji.12105