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Amino Acids as Building Blocks for Carbonic Anhydrase Inhibitors.
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- Metabolites (2218-1989), 2018, v. 8, n. 2, p. 36, doi. 10.3390/metabo8020036
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- Article
Overcoming Multidrug Resistance (MDR): Design, Biological Evaluation and Molecular Modelling Studies of 2,4‐Substituted Quinazoline Derivatives.
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- ChemMedChem, 2022, v. 17, n. 12, p. 1, doi. 10.1002/cmdc.202200027
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- Article
Two types of interneurons in the mouse lateral geniculate nucleus are characterized by different h-current density.
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- Scientific Reports, 2016, p. 24904, doi. 10.1038/srep24904
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- Article
Effectiveness of the Histone Deacetylase Inhibitor (S)-2 against LNCaP and PC3 Human Prostate Cancer Cells.
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- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058267
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- Article
Sigma Receptor Binding Profile of a Series of Analgesic Tropane Derivatives.
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- Archiv der Pharmazie, 2002, v. 335, n. 1, p. 39, doi. 10.1002/1521-4184(200201)335:1<39::AID-ARDP39>3.0.CO;2-H
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- Article
Reduced Flexibility Analogs of Analgesic and Cognition Enhancing α-Tropanyl Esters.
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- Archiv der Pharmazie, 1996, v. 329, n. 2, p. 105, doi. 10.1002/ardp.19963290208
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- Article
Synthesis of Hexahydro-2-pyrindine (=Hexahydrocyclopenta[ c]pyridine) Derivatives as Conformationally Restricted Analogs of the Nicotinic Ligands Arecolone and Isoarecolone.
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- Helvetica Chimica Acta, 2002, v. 85, n. 1, p. 96, doi. 10.1002/1522-2675(200201)85:1<96::AID-HLCA96>3.0.CO;2-7
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- Article
Dual Inhibitors of P-gp and Carbonic Anhydrase XII (hCA XII) against Tumor Multidrug Resistance with Piperazine Scaffold †.
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- Molecules, 2024, v. 29, n. 14, p. 3290, doi. 10.3390/molecules29143290
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- Article
Synthetic Approaches to Piperazine-Containing Drugs Approved by FDA in the Period of 2011–2023 †.
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- Molecules, 2024, v. 29, n. 1, p. 68, doi. 10.3390/molecules29010068
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- Article
Recent Advances in the Discovery of Nicotinic Acetylcholine Receptor Allosteric Modulators.
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- Molecules, 2023, v. 28, n. 3, p. 1270, doi. 10.3390/molecules28031270
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- Article
New Histamine-Related Five-Membered N-Heterocycle Derivatives as Carbonic Anhydrase I Activators.
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- Molecules, 2022, v. 27, n. 2, p. 545, doi. 10.3390/molecules27020545
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- Article
HDAC-inhibitor (S)-8 disrupts HDAC6- PP1 complex prompting A375 melanoma cell growth arrest and apoptosis.
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- Journal of Cellular & Molecular Medicine, 2015, v. 19, n. 1, p. 143, doi. 10.1111/jcmm.12345
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- Article
Selective Blockade of HCN1/HCN2 Channels as a Potential Pharmacological Strategy Against Pain.
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- Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01252
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- Article
The Hyperpolarization-Activated HCN4 Channel is Important for Proper Maintenance of Oscillatory Activity in the Thalamocortical System.
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- Cerebral Cortex, 2019, v. 29, n. 5, p. 2291, doi. 10.1093/cercor/bhz047
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- Article
Hyperpolarization-activated cyclic-nucleotide-gated channels: pathophysiological, developmental, and pharmacological insights into their function in cellular excitability1.
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- Canadian Journal of Physiology & Pharmacology, 2018, v. 96, n. 10, p. 977, doi. 10.1139/cjpp-2018-0115
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- Article
Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats.
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- Cells (2073-4409), 2021, v. 10, n. 10, p. 2540, doi. 10.3390/cells10102540
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- Article
Novel blockers of hyperpolarization-activated current with isoform selectivity in recombinant cells and native tissue.
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- British Journal of Pharmacology, 2012, v. 166, n. 2, p. 602, doi. 10.1111/j.1476-5381.2011.01782.x
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- Article
Chiral synthesis and pharmacological evaluation of the enantiomers of SM<sub>32</sub>, a new analgesic and cognition-enhancing agent.
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- Chirality, 1996, v. 8, n. 8, p. 579, doi. 10.1002/(SICI)1520-636X(1996)8:8<579::AID-CHIR7>3.0.CO;2-4
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- Article
Memantine Derivatives as Multitarget Agents in Alzheimer's Disease.
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- Molecules, 2020, v. 25, n. 17, p. 4005, doi. 10.3390/molecules25174005
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Novel Multitarget Therapies for Lung Cancer and Respiratory Disease.
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- Molecules, 2020, v. 25, n. 17, p. 3987, doi. 10.3390/molecules25173987
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- Article
Properly Substituted Cyclic Bis-(2-bromobenzylidene) Compounds Behaved as Dual p300/CARM1 Inhibitors and Induced Apoptosis in Cancer Cells.
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- Molecules, 2020, v. 25, n. 14, p. 3122, doi. 10.3390/molecules25143122
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Multi-Targeting Bioactive Compounds Extracted from Essential Oils as Kinase Inhibitors.
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- Molecules, 2020, v. 25, n. 9, p. 2174, doi. 10.3390/molecules25092174
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- Article
Binding-Site Match Maker (BSMM): A Computational Method for the Design of Multi-Target Ligands.
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- Molecules, 2020, v. 25, n. 8, p. 1821, doi. 10.3390/molecules25081821
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- Article
Dual P-Glycoprotein and CA XII Inhibitors: A New Strategy to Reverse the P-gp Mediated Multidrug Resistance (MDR) in Cancer Cells †.
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- Molecules, 2020, v. 25, n. 7, p. 1748, doi. 10.3390/molecules25071748
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- Article
Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels.
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- Molecules, 2020, v. 25, n. 6, p. 1329, doi. 10.3390/molecules25061329
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- Article
Biological Activity Profiles of Multitarget Ligands from X-ray Structures.
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- Molecules, 2020, v. 25, n. 4, p. 794, doi. 10.3390/molecules25040794
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Identifying Promiscuous Compounds with Activity against Different Target Classes.
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- Molecules, 2019, v. 24, n. 22, p. 4185, doi. 10.3390/molecules24224185
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- Article
Structure-Activity Relationship Studies on 6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline Derivatives as Multidrug Resistance Reversers.
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- ChemMedChem, 2017, v. 12, n. 16, p. 1369, doi. 10.1002/cmdc.201700239
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- Article
Arylamino Esters As P-Glycoprotein Modulators: SAR Studies to Establish Requirements for Potency and Selectivity.
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- ChemMedChem, 2015, v. 10, n. 8, p. 1339, doi. 10.1002/cmdc.201500143
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- Article