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- Title
Antibacterial activities of zinc oxide and Mn-doped zinc oxide synthesized using Melastoma malabathricum (L.) leaf extract.
- Authors
Khan, Mohammad Mansoob; Harunsani, Mohammad Hilni; Tan, Ai Ling; Hojamberdiev, Mirabbos; Azamay, Syafiqah; Ahmad, Norhayati
- Abstract
Zinc oxide (ZnO) is considered as a potential antimicrobial agent. This work aims to investigate the properties of ZnO and Mn-doped ZnO (1% and 5%) fabricated using aqueous leaf extract of Melastoma malabathricum via green synthesis and its antibacterial activities. The synthesized ZnO and Mn-doped ZnO were characterized using different techniques such as powder X-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy and UV–Vis diffuse reflectance spectroscopy. The synthesized ZnO and Mn-doped ZnO were tested for its antibacterial properties on two Gram-negative bacteria: Escherichia coli and Pseudomonas aeruginosa, and two Gram-positive bacteria: Bacillus subtilis and Staphylococcus aureus. The results showed positive antibacterial effects for B. subtilis and S. aureus only. Among the three materials tested, 1% Mn-doped ZnO exhibited the highest antibacterial activity for B. subtilis with the minimum inhibitory concentration being 50 mg/mL.
- Subjects
ZINC oxide synthesis; ZINC oxide; INHIBITORY Concentration 50; PSEUDOMONAS aeruginosa; X-ray photoelectron spectroscopy; STAPHYLOCOCCUS aureus; X-ray powder diffraction; GRAM-positive bacteria
- Publication
Bioprocess & Biosystems Engineering, 2020, Vol 43, Issue 8, p1499
- ISSN
1615-7591
- Publication type
Article
- DOI
10.1007/s00449-020-02343-3