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- Title
En bloc liver and pancreas transplantation after total pancreatectomy with autologous islet transplantation.
- Authors
Generette, Gabriela S.; Bachul, Piotr J.; Golab, Karolina; Basto, Lindsay; Pyda, Jordan S.; Borek, Peter; Tibudan, Martin; Anteby, Roi; Perea, Laurencia; Charlton, Michael; Perez-Gutierrez, Angelica; Jayant, Kumar; Lucander, Aaron; Matthews, Jeffrey B.; Millis, J. Michael; John Fung; Witkowski, Piotr
- Abstract
We present a patient with intractable and debilitating pain secondary to chronic pancreatitis who was effectively treated with total pancreatectomy with islet autotransplantation (TPIAT). Islets engrafted into his liver significantly contributed to improved blood glucose control and quality of life. Subsequently, the patient developed alcohol related acute liver failure and en bloc liver and pancreas transplantation was performed to replace the failing liver with engrafted islets. Pancreas transplantation was required to resolve his life-threatening severe hypoglycemic episodes. Herein, we detail an innovative and multidisciplinary management of this complex medical problem.
- Subjects
PANCREAS transplantation; PANCREATECTOMY; TRANSPLANTATION immunology; BLOOD sugar; QUALITY of life
- Publication
European Journal of Translational & Clinical Medicine, 2020, Vol 3, Issue 2, p11
- ISSN
2657-3148
- Publication type
Article
- DOI
10.31373/ejtcm/130187