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- Title
Multicenter 1-month follow-up study of the patch test reaction to the gold sodium thiosulfate of the TRUE Test and its association with piercings and dental metal history.
- Authors
Kayoko Suzuki; Kayoko Matsunaga; Akiko Ito; Akiko Yagami; Takashi Ito; Hitoshi Miyazawa; Mariko Sugiura; Atsuko Adachi; Yumiko Kubota; Yuko Watanabe; Atsuko Kato; Kazue Nishioka; Atsushi Fukunaga; Masako Mochizuki; Yuko Ikezawa; Takahiko Tsunoda; Kaoru Takayama; Kumiko Washizaki; Hiroo Yokozeki; Takuma Ishihara
- Abstract
Background: There is controversy over late and long-lasting reactions to gold sodium thiosulfate (GST). Objectives: To study the GST patch test reaction by observing the application site after 1 month, and to clarify the relevance of GST sensitization by piercings and dental metals. Patients: A retrospective analysis was performed on 746 patients (143 male; 603 female) who were patch tested using GST of the TRUE Test. We conducted a questionnaire on the presence of piercings or dental metals in these patients. Results: The GST positive rate was 27.9% at day (D)3 and/or D7 and 40.3% up to the 1-month reading. The positive rate was significantly higher in female patients and increased with age. Sixty-two percent of cases with a positive reaction at D7 continued to show a positive reaction after 1 month. Eleven percent of cases with a negative reaction at D3 and D7 showed a late reaction. Both piercings and dental metals were related to gold sensitization. Conclusions: The GST of the TRUE Test had a high positive and low false-negative rate. The 1-month reading after the patch test was important for identifying late reactions. Piercing history and dental metal were associated with gold sensitization.
- Subjects
DENTAL metallurgy; THIOSULFATES; GOLD; WOMEN patients; QUESTIONNAIRES
- Publication
Contact Dermatitis (01051873), 2021, Vol 85, Issue 2, p154
- ISSN
0105-1873
- Publication type
Article
- DOI
10.1111/cod.13827