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- Title
Prodromal angina is associated with myocardial salvage in acute ST-segment elevation myocardial infarction.
- Authors
Masci, Pier Giorgio; Andreini, Daniele; Francone, Marco; Bertella, Erika; De Luca, Laura; Coceani, Michele; Mushtaq, Saima; Mariani, Massimiliano; Carbone, Iacopo; Pontone, Gianluca; Agati, Luciano; Bogaert, Jan; Lombardi, Massimo
- Abstract
Aims Previous studies have shown that prodromal angina (PA) occurs frequently in acute myocardial infarction (MI) patients. However, the potential benefits of PA on ischaemic myocardial damage remain unknown. Methods and results One-hundred and fifty-four patients with acute ST-segment elevation MI successfully treated with primary percutaneous coronary intervention (PPCI) were prospectively evaluated for new-onset PA in the week preceding infarction and other factors known to influence myocardial salvage. Cardiovascular magnetic resonance was performed 8 ± 3 days after MI for the assessment of area-at-risk (AAR), MI size, myocardial haemorrhage (MH), microvascular obstruction (MO), and myocardial salvage index (MSI). Conclusion In acute MI patients, new-onset PA is associated with higher MSI independent of others factors known to influence jeopardized myocardium, as well as with less microvascular damage.
- Subjects
ANGINA pectoris; CORONARY heart disease surgery; DIAGNOSIS of diabetes; HYPERTENSION; CARDIOVASCULAR disease diagnosis; ISCHEMIA diagnosis; MYOCARDIAL infarction diagnosis; MYOCARDIAL infarction risk factors; CARDIOMYOPATHIES; CORONARY arteries; MYOCARDIUM; ADRENERGIC beta agonists; ANGIOGRAPHY; CARDIAC catheterization; CARDIOTONIC agents; CHI-squared test; ELECTROCARDIOGRAPHY; FISHER exact test; HEMODYNAMICS; MORPHINE; MYOCARDIAL infarction; MYOCARDIAL revascularization; NITRATES; SMOKING; TRANSLUMINAL angioplasty; U-statistics; COMORBIDITY; DATA analysis; PATIENT selection; DATA analysis software; DESCRIPTIVE statistics; ANATOMY; DIAGNOSIS
- Publication
European Heart Journal - Cardiovascular Imaging, 2013, Vol 14, Issue 11, p1041
- ISSN
2047-2404
- Publication type
Article
- DOI
10.1093/ehjci/jet063