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- Title
Expression Of Leptin In Human Saliva After Orthodontic Force And Its Relationship With Body Mass Index.
- Authors
jayachandran, Tamizhmani; sikri, Ankit; Vijayadhith; roy, Rahul; Shah, Akash B.; P. V., Swathi
- Abstract
Introduction: The Aim of this study is to compare the concentration of salivary leptin levels between underweight and normal weight individuals and its significance in orthodontic tooth movement. Materials and Method: This observational study included forty-five underweight and normal weight female subjects and they are divided into two groups, group I (underweight) and group II (normal weight) depending on their mean body mass index given by WHO classification. All subjects underwent upper first premolar extraction, and distal force is applied with lacebacks to maxillary canine. Salivary leptin samples were collected before force application (To), one hour after appliance placement (T1), and one month after appliance placement (T2). Result: Underweight individuals show decreased salivary leptin concentration than normal weight individuals. Orthodontic tooth movement is increased in underweight individuals when compared with normal weight individuals. Conclusion: Orthodontic tooth movement is increased in underweight patients when compared with normal weight patients. Salivary leptin is two times greater in normal weight patients when compared with underweight patients.
- Subjects
SALIVARY glands; BODY mass index; LEPTIN; SALIVA; CORRECTIVE orthodontics
- Publication
Journal of Pharmaceutical Negative Results, 2022, Vol 13, p920
- ISSN
0976-9234
- Publication type
Article
- DOI
10.47750/pnr.2022.13.S05.146