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- Title
Assessment of the pre-emptive effect of photobiomodulation in the postoperative period of impacted lower third molar extractions: A randomized, controlled, double-blind study protocol.
- Authors
Salaberry, Daniel Rodríguez; Bruno, Laura Hermida; Cirisola, Rolf Wilhem Consolandich; Longo, Priscila Larcher; Chavantes, Maria Cristina; Navarro, Ricardo Scarparo; Gonçalves, Marcela Letícia Leal; Sobral, Ana Paula Taboada; Gimenez, Thais; Duran, Cinthya Cosme Gutierrez; Motta, Lara Jansiski; Bussadori, Sandra Kalil; Horliana, Anna Carolina Ratto Tempestini; Mesquita Ferrari, Raquel Agnelli; Fernandes, Kristianne Porta Santos
- Abstract
Photobiomodulation is a safe option for controlling pain, edema, and trismus when applied postoperatively in third molar surgery. However, administration prior to surgery has been under-explored. This study aims to explore the effectiveness of pre-emptive photobiomodulation in reducing postoperative edema in impacted lower third molar extractions. Two groups of healthy individuals undergoing tooth extraction will be randomly assigned: Control group receiving pre-emptive corticosteroid and simulated photobiomodulation, and Photobiomodulation Group receiving intraoral low-intensity laser and extraoral LED cluster application. The primary outcome will be postoperative edema after 48 h. The secondary outcomes will be pain, trismus dysphagia, and analgesic intake (paracetamol). These outcomes will be assessed at baseline as well as two and seven days after surgery. Adverse effects will be recorded. Data will be presented as means ± SD and a p-value < 0.05 will be indicative of statistical significance.
- Subjects
THIRD molars; PHOTOBIOMODULATION therapy; POSTOPERATIVE period; RESEARCH protocols; DENTAL extraction; TOOTH socket; TRISMUS
- Publication
PLoS ONE, 2024, Vol 19, Issue 6, p1
- ISSN
1932-6203
- Publication type
Article
- DOI
10.1371/journal.pone.0300136