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- Title
Respiratory Syncytial Virus Pneumonia in Hospitalized Adult Patients with Leukemia.
- Authors
Whimbey, Estella; Couch, Robert B.; Englund, Janet A.; Andreeff, Michael; Goodrich, James M.; Raad, Issam I.; Lewis, Victor; Mirza, Nadeem; Luna, Mario A.; Baxter, Barbara; Tarrand, Jeffrey J.; Bodey, Gerald P.
- Abstract
Respiratory syncytial virus (RSV) has been demonstrated to be an important cause of life-threatening pneumonia in adult bone marrow transplant recipients; however, its role in other immunocom-promised adults has not been defined. We prospectively studied all adult patients with leukemia who were hospitalized at M. D. Anderson Cancer Center (Houston) during a 1-year period (November 1993 through October 1994). During a 19-week period when RSV was prevalent in the community, it was isolated from 9 (10%) of 87 patients with leukemia who developed an acute respiratory illness. In 6 (75%) of 8 patients with profound chemotherapy-induced myelosuppression, the RSV infection was complicated by pneumonia, with an 83% mortality rate. RSV appears to be an important cause of severe and often fatal pneumonia in myelosuppressed patients with leukemia.
- Publication
Clinical Infectious Diseases, 1995, Vol 21, Issue 2, p376
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/clinids/21.2.376