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Human cyclophilin 40 unravels neurotoxic amyloids.
- Published in:
- PLoS Biology, 2017, v. 15, n. 6, p. 1, doi. 10.1371/journal.pbio.2001336
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- Publication type:
- Article
Selectively Reduced Expression of Synaptic Plasticity-Related Genes in Amyloid Precursor Protein + Presenilin-1 Transgenic Mice.
- Published in:
- Journal of Neuroscience, 2003, v. 23, n. 12, p. 5219, doi. 10.1523/JNEUROSCI.23-12-05219.2003
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- Publication type:
- Article
P3‐205: AN EMERGING ROLE FOR HSP27 IN VASCULAR COGNITIVE IMPAIRMENT AND DEMENTIA (VCID).
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1146, doi. 10.1016/j.jalz.2018.06.1564
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- Publication type:
- Article
P1‐231: PROLYL‐ISOMERASES UNTANGLE TAU AGGREGATES AND PREVENT TAU PATHOLOGY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P367, doi. 10.1016/j.jalz.2018.06.236
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- Publication type:
- Article
Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 2, p. 851, doi. 10.3390/ijms23020851
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- Publication type:
- Article
Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 15, p. 5442, doi. 10.3390/ijms21155442
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- Publication type:
- Article
Early Life Stress and High FKBP5 Interact to Increase Anxiety-Like Symptoms through Altered AKT Signaling in the Dorsal Hippocampus.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 11, p. 2738, doi. 10.3390/ijms20112738
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- Publication type:
- Article
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.
- Published in:
- Journal of Clinical Investigation, 2013, v. 123, n. 10, p. 4158, doi. 10.1172/JCI69003
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- Publication type:
- Article
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins.
- Published in:
- 2007
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- Publication type:
- journal article
Spermidine/spermine-N<sup>1</sup>-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.
- Published in:
- Alzheimer's Research & Therapy, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13195-019-0507-y
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- Publication type:
- Article
AHA1 ACCELERATES HSP90 ATPASE ACTIVITY TO DRIVE TAU AGGREGATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P556, doi. 10.1016/j.jalz.2017.07.159
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- Publication type:
- Article
PPID CONTROLS TOXIC AMYLOID FORMATION THROUGH PROLINE ISOMERIZATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P671, doi. 10.1016/j.jalz.2017.06.819
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- Publication type:
- Article
PROLINE ISOMERIZATION CONTROLS TOXIC AMYLOID FORMATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1297, doi. 10.1016/j.jalz.2017.06.1969
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- Publication type:
- Article
HSC70/DNAJC5 COMPLEXES CONTROL THE RELEASE OF EXTRACELLULAR NEURODEGENERATIVE PROTEINS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P341, doi. 10.1016/j.jalz.2016.06.628
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- Publication type:
- Article
Targeting chaperones to treat ftld.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P201, doi. 10.1016/j.jalz.2014.04.245
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- Publication type:
- Article
Endoplasmic reticulum (ER) stress and abnormal tau converge in a ubiquitin-related vicious cycle: Early events in neuronal damage
- Published in:
- 2012
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- Publication type:
- Abstract
FKBP51 connects tau to the systemic stress response network through Hsp90
- Published in:
- 2012
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- Publication type:
- Abstract
Exploiting the diversity of the chaperone repertoire to treat tauopathies
- Published in:
- 2011
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- Publication type:
- Abstract
Neuronal tau-specific stress induction of molecular chaperones: The failure of a coping mechanism
- Published in:
- 2011
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- Publication type:
- Abstract
Chaperone-mediated modulation of tau aggregation correlates with modifications in tau pathology and synaptic plasticity
- Published in:
- 2010
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- Publication type:
- Abstract
The early involvement of chaperones in tau pathogenesis
- Published in:
- 2010
- By:
- Publication type:
- Abstract
Chemical manipulation of Hsp70 activity regulates tau processing
- Published in:
- 2009
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- Publication type:
- Abstract
P2-141: Unraveling the process of tau hyperphosphorylation one gene at a time
- Published in:
- 2008
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- Publication type:
- Abstract
O1-06-03: Akt functions to regulate the chaperone complex and attenuate Tau degradation
- Published in:
- 2008
- By:
- Publication type:
- Abstract
Commentary on “Cytoskeletal modulators and pleiotropic strategies for Alzheimer drug discovery.” The last stand: The dichotomy of chaperone function in Alzheimer’s disease
- Published in:
- 2007
- By:
- Publication type:
- Editorial
P3-319: Manipulating components of the heat shock response as a therapeutic strategy for tauopathies
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P3-294: The impact of chip on neurodegenerative diseases
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P3-319: Manipulating components of the heat shock response as a therapeutic strategy for tauopathies
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P3-294: The impact of chip on neurodegenerative diseases
- Published in:
- 2006
- By:
- Publication type:
- Abstract
Duration and Specificity of Humoral Immune Responses in Mice Vaccinated with the Alzheimer's Disease-Associated β-Amyloid 1-42 Peptide.
- Published in:
- DNA & Cell Biology, 2001, v. 20, n. 11, p. 723, doi. 10.1089/10445490152717587
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- Publication type:
- Article
Number of Aβ Inoculations in APP+PS1 Transgenic Mice Influences Antibody Titers, Microglial Activation, and Congophilic Plaque Levels.
- Published in:
- DNA & Cell Biology, 2001, v. 20, n. 11, p. 731, doi. 10.1089/10445490152717596
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- Publication type:
- Article
Murine Monoclonal Antibodies Biologically Active against the Amino Region of HIV-1 gp120: Isolation and Characterization.
- Published in:
- DNA & Cell Biology, 2000, v. 19, n. 4, p. 243, doi. 10.1089/104454900314519
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- Publication type:
- Article
A global view of Hsp90 functions.
- Published in:
- Nature Structural & Molecular Biology, 2013, v. 20, n. 1, p. 1, doi. 10.1038/nsmb.2481
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- Publication type:
- Article
Neuronal Life Span Versus Health Span: Principles of Natural Selection at Work in the Degenerating Brain.
- Published in:
- Journal of Molecular Neuroscience, 2011, v. 45, n. 3, p. 467, doi. 10.1007/s12031-011-9540-4
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- Publication type:
- Article
Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0186-2
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- Publication type:
- Article
Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0186-2
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- Publication type:
- Article
Age-Associated Epigenetic Upregulation of the FKBP5 Gene Selectively Impairs Stress Resiliency.
- Published in:
- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107241
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- Publication type:
- Article
Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance.
- Published in:
- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035566
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- Publication type:
- Article
Adeno-Associated Virus-Mediated Rescue of the Cognitive Defects in a Mouse Model for Angelman Syndrome.
- Published in:
- PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0027221
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- Publication type:
- Article
A New Anti-Depressive Strategy for the Elderly: Ablation of FKBP5/FKBP51.
- Published in:
- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024840
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- Publication type:
- Article
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy.
- Published in:
- Neurodegenerative Diseases, 2013, v. 11, n. 4, p. 165, doi. 10.1159/000337230
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- Publication type:
- Article
Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06880-0
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- Publication type:
- Article
Trafficking CD11b-Positive Blood Cells Deliver Therapeutic Genes to the Brain of Amyloid-Depositing Transgenic Mice.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 29, p. 9651, doi. 10.1523/JNEUROSCI.0329-10.2010
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- Publication type:
- Article
The Hsp90 Cochaperone, FKBP51, Increases Tau Stability and Polymerizes Microtubules.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 2, p. 591, doi. 10.1523/JNEUROSCI.4815-09.2010
- By:
- Publication type:
- Article
Chemical Manipulation of Hsp70 ATPase Activity Regulates Tau Stability.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 39, p. 12079, doi. 10.1523/JNEUROSCI.3345-09.2009
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- Publication type:
- Article
Progranulin Mediates Caspase-Dependent Cleavage of TAR DNA Binding Protein-43.
- Published in:
- Journal of Neuroscience, 2007, v. 27, n. 39, p. 10530, doi. 10.1523/JNEUROSCI.3421-07.2007
- By:
- Publication type:
- Article
Deletion of the Ubiquitin Ligase CHIP Leads to the Accumulation, But Not the Aggregation, of Both Endogenous Phospho- and Caspase-3-Cleaved Tau Species.
- Published in:
- Journal of Neuroscience, 2006, v. 26, n. 26, p. 6985, doi. 10.1523/JNEUROSCI.0746-06.2006
- By:
- Publication type:
- Article
DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins.
- Published in:
- EMBO Journal, 2016, v. 35, n. 14, p. 1537, doi. 10.15252/embj.201593489
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- Publication type:
- Article
LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice.
- Published in:
- 2010
- By:
- Publication type:
- journal article
LPS- induced inflammation exacerbates phosphotau pathology in rTg4510 mice.
- Published in:
- Journal of Neuroinflammation, 2010, v. 7, p. 56, doi. 10.1186/1742-2094-7-56
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- Publication type:
- Article