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- Title
Group B streptococcus infections of soft tissue and bone in California adults, 1995-2012.
- Authors
SMITH, E. M.; KHAN, M. A.; REINGOLD, A.; WATT, J. P.
- Abstract
Group B streptococcus (GBS) is an increasing cause of disease in adults. We present long-term trends in incidence of overall infections and identify characteristics of patients with GBS cellulitis, bone and joint infections. Active, population-based surveillance was conducted from 1995–2012 in three California counties and the data were analysed retrospectively. All cases had isolation of GBS from a normally sterile site. Cases of cellulitis were classified based on clinical diagnosis. GBS bone or joint infection was defined as isolation of GBS from a bone or joint or a diagnosis of osteomyelitis or septic arthritis. Medical charts were reviewed for demographic and clinical information. There were 3917 cases of GBS; the incidence of disease increased from 5·8 to 8·3 cases/100 000 persons (P < 0·001) from 1995 to 2012. In adults aged ⩾40 years, the overall incidence of GBS increased from 8·5 to 14·2 cases/100 000 (P < 0·001) persons during the study period. The incidence of cellulitis increased from 1·6 to 3·8 cases/100 000 (P < 0·001), bone infection increased from 0·7 to 2·6 cases/100 000 (P < 0·001), and the incidence of joint infection remained approximately constant at an average rate of 1·0 case/100 000. The highest incidence rates were observed in men, persons aged ⩾80 years, non-Hispanic blacks and Hispanics. Diabetes was the most common underlying condition (51·2% cellulitis cases, 76·3% bone infections, 29·8% joint infections).
- Subjects
CALIFORNIA; STREPTOCOCCUS agalactiae; SOFT tissue infections; DISEASES in adults; ETIOLOGY of diseases; CELLULITIS; BONE diseases; SKIN infections; STREPTOCOCCAL diseases; PATIENTS; EPIDEMIOLOGY; INFECTIOUS arthritis; LONGITUDINAL method; OSTEOMYELITIS; RESEARCH funding; STREPTOCOCCUS
- Publication
Epidemiology & Infection, 2015, Vol 143, Issue 15, p3343
- ISSN
0950-2688
- Publication type
journal article
- DOI
10.1017/S0950268815000606