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- Title
Convolutional neural network-based kidney volume estimation from low-dose unenhanced computed tomography scans.
- Authors
Müller, Lukas; Tibyampansha, Dativa; Mildenberger, Peter; Panholzer, Torsten; Jungmann, Florian; Halfmann, Moritz C.
- Abstract
Purpose: Kidney volume is important in the management of renal diseases. Unfortunately, the currently available, semi-automated kidney volume determination is time-consuming and prone to errors. Recent advances in its automation are promising but mostly require contrast-enhanced computed tomography (CT) scans. This study aimed at establishing an automated estimation of kidney volume in non-contrast, low-dose CT scans of patients with suspected urolithiasis. Methods: The kidney segmentation process was automated with 2D Convolutional Neural Network (CNN) models trained on manually segmented 2D transverse images extracted from low-dose, unenhanced CT scans of 210 patients. The models' segmentation accuracy was assessed using Dice Similarity Coefficient (DSC), for the overlap with manually-generated masks on a set of images not used in the training. Next, the models were applied to 22 previously unseen cases to segment kidney regions. The volume of each kidney was calculated from the product of voxel number and their volume in each segmented mask. Kidney volume results were then validated against results semi-automatically obtained by radiologists. Results: The CNN-enabled kidney volume estimation took a mean of 32 s for both kidneys in a CT scan with an average of 1026 slices. The DSC was 0.91 and 0.86 and for left and right kidneys, respectively. Inter-rater variability had consistencies of ICC = 0.89 (right), 0.92 (left), and absolute agreements of ICC = 0.89 (right), 0.93 (left) between the CNN-enabled and semi-automated volume estimations. Conclusion: In our work, we demonstrated that CNN-enabled kidney volume estimation is feasible and highly reproducible in low-dose, non-enhanced CT scans. Automatic segmentation can thereby quantitatively enhance radiological reports. Key points: • CNN-enabled kidney volume estimation is highly reproducible in low-dose, non-enhanced CT scans. • CNN-enabled volume estimation required a fraction of time required by semi-automatic segmentations. • Development of CNN-based models can be facilitated by pre-existing structured reporting environments.
- Subjects
CABLE News Network; CONVOLUTIONAL neural networks; COMPUTED tomography; KIDNEYS; KIDNEY diseases
- Publication
BMC Medical Imaging, 2023, Vol 23, Issue 1, p1
- ISSN
1471-2342
- Publication type
Article
- DOI
10.1186/s12880-023-01142-y