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- Title
Detection of DNA of six human herpesviruses in the cerebrospinal fluid of immunocompetent non-herpetic acute limbic encephalitis patients.
- Authors
Yoshikawa, Tetsushi; Asano, Yoshizo; Takahashi, Yukitoshi
- Abstract
In order to determine whether six other human herpesviruses, aside from herpes simplex virus, are associated with non-herpetic acute limbic encephalitis in immunocompetent individuals, real-time PCR was used to detect the DNA of herpesviruses in CSF collected from 61 patients with this form of encephalitis. Five of the human herpesviruses tested were not detected in any of the 61 CSF samples. EBV DNA was detected in one CSF sample. The EBV DNA-positive patient was a 36-year-old woman who presented with fever, headache, mild somnolence, and the typical neuroimaging findings.
- Subjects
HERPESVIRUSES; CEREBROSPINAL fluid examination; IMMUNOCOMPETENT cells; ENCEPHALITIS; POLYMERASE chain reaction; DNA; BRAIN imaging; PATIENTS
- Publication
Microbiology & Immunology, 2010, Vol 54, Issue 8, p471
- ISSN
0385-5600
- Publication type
Article
- DOI
10.1111/j.1348-0421.2010.00234.x