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- Title
Impact of the COVID-19 Pandemic on Cervical Cancer Screening in São Paulo State, Brazil.
- Authors
Martins, Toni Ricardo; Witkin, Steven S.; Mendes-Corrêa, Maria Cássia; Godoy, Amanda Scancella de; Cury, Lise; Balancin, Marcelo Luiz; Ab'Saber, Alexandre Muxfeldt; Peres, Stela Verzinhasse; Messias, Sandra; Tozetto Mendoza, Tânia Regina; Longatto-Filho, Adhemar
- Abstract
Introduction: The early identification of precursor lesions followed by appropriate treatment prevents development of cervical cancer and its consequences. Objective: The present study evaluated the influence of the COVID-19 pandemic on cervical cancer screening by comparing the quantity of tests to detect cervical cellular changes performed in São Paulo state in 2019, prior to the detection of SARS-CoV-2 in Brazil, to the first (2020) and second (2021) years following its appearance. Materials and Methods: Data from Fundação Oncocentro de São Paulo (FOSP), the agency that analyses approximately 220,000 Papanicolaou (Pap) tests annually, were reviewed. Results: A median of 1,835 Pap tests were performed in 55 municipalities in 2019. This was reduced to 815 tests in 2020, a 56% decrease (p = 0.0026). In 2021, the median number was 1,745, a 53% increase over 2020 levels (p = 0.0233). The 26 municipalities with >1,000 tests in 2020 had a median reduction from 4,433 in 2019 to 2,580 in 2020 (p = 0. 0046). The 29 municipalities with <1,000 tests had a median reduction from 951 in 2019 to 554 in 2020 (p < 0.0001). There was a 44% reduction in the number of follow-up cytological evaluations from 2019 to 2020, followed by a 30% increase in the following year. However, the percentage of women with a normal finding or with any abnormality remained unchanged. The findings from a histological evaluation of women in São Paulo city indicated that the percent of cases positive for CIN-1 (p < 0.0410) and CIN-3 (p < 0.0012) increased in 2020 and 2021 as compared to 2019 levels. Conclusion: A reduction in testing for cervical cancer in the first year of the COVID-19 pandemic, accompanied by an elevated incidence of precancerous lesions in each of the first 2 years following its initiation, may portend a subsequent increased occurrence of cervical cancer in Brazil.
- Subjects
BRAZIL; OPPORTUNISTIC infections; WORLD Health Organization; EARLY detection of cancer; PAP test; RISK assessment; COMPARATIVE studies; DESCRIPTIVE statistics; CERVIX uteri tumors; COVID-19 pandemic; PRECANCEROUS conditions; DISEASE risk factors
- Publication
Acta Cytologica, 2023, Vol 67, Issue 4, p388
- ISSN
0001-5547
- Publication type
Article
- DOI
10.1159/000529249