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- Title
Histologic Evaluation of rhBMP-2 in an Extraction Site Model in the Esthetic Zone: A Series of 16 Cases Preparing for Implant Placement.
- Authors
Scheyer, E. Todd; Lipton, David I.; McGuire, Michael K.; Calahan, Blaine G.; Demetter, Randy S.; Mealey, Brian L.
- Abstract
Growth factors have been used in numerous oral applications to aid in bone formation after tooth extraction. Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-b superfamily and are involved in the differentiation of pluripotent mesenchymal cells, leading to new bone formation through osteoblastic induction. This study examined histologic wound healing following extraction and ridge preservation using recombinant human BMP-2 (rhBMP-2) and a collagen sponge. Formation of new vital bone was seen, suggesting that this material is a viable option for ridge preservation in preparation for implant placement.
- Subjects
BONE growth; BONE morphogenetic proteins; COSMETIC dentistry; DENTAL implants; WOUND healing
- Publication
International Journal of Periodontics & Restorative Dentistry, 2020, Vol 40, Issue 2, p171
- ISSN
0198-7569
- Publication type
Article
- DOI
10.11607/prd.4535