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- Title
Xylitol: Effects on the Acquisition of Cariogenic Species in Infants.
- Authors
Fontana, Margherita; Catt, Diana; Eckert, George J.; Ofner, Susan; Toro, Milagros; Gregory, Richard L.; Zandona, Andrea Ferreira; Eggertsson, Hafsteinn; Jackson, Richard; Chin, Judith; Zero, Domenick; Sissons, Christopher H.
- Abstract
Purpose: The purpose of this study was to examine the effects of xylitol gum (XG) on the acquisition pattern of 39 bacterial species, including mutans streptococci (MS), in infants. Methods: Ninety-seven mothers (MS counts > 105 CFU/ml) were randomly divided into 4 groups and received: 1) XG (4.2 gm/day); 2) XG (6 months after baseline exams); 3) sorbitol gum (4.2 gm/day); or 4) no gum. Groups 1 and 3 chewed gum 3 times a day for 9 months. Microbiota of plaque and saliva samples from the mother-child pairs were analyzed by culturing and via checkerboard DNA-DNA hybridization. Results: MS was isolated from 33% of the predentate infant (≤5 months old) baseline saliva samples and from 41% of the saliva and 65% of the plaque samples at the final visit. At baseline, positive responses to "mother's checking of baby's food temperature using baby's spoon" and "starting a bottle after stopping breast-feeding" were significant predictors (P=.009 and P<.001, respectively) of infant's total streptococci counts. At the final visit (9 months later), there were no significant differences between treatment groups for infants' 39 microbial plaque species, including MS. Conclusions: Maternal use of xylitol gum did not result in statistically significant differences in the microbial plaque composition of 9- to 14-month-old infants.
- Subjects
XYLITOL; INFANTS; SALIVA; DENTAL plaque; STREPTOCOCCUS mutans; DNA; NUCLEIC acid hybridization; MOTHER-infant relationship
- Publication
Pediatric Dentistry, 2009, Vol 31, Issue 3, p257
- ISSN
0164-1263
- Publication type
Article