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- Title
Prevalence of deep venous thrombosis detected by ultrasonography before surgery in patients with gastric cancer: a retrospective study of 1140 consecutive patients.
- Authors
Tanizawa, Yutaka; Bando, Etsuro; Kawamura, Taiichi; Tokunaga, Masanori; Makuuchi, Rie; Iida, Kei; Nanri, Kazuhide; Yoneyama, Masashi; Terashima, Masanori
- Abstract
Background: The prevalence of deep venous thrombosis (DVT) in patients with gastric cancer before surgery is unknown. This study aimed to clarify the risk factors for DVT of the lower extremities in patients with gastric cancer before surgery and to evaluate the usefulness of ultrasonographic screening for prevention of postoperative pulmonary thromboembolism (PTE). Methods: Patients who had undergone lower-extremity venous ultrasonography before surgery for gastric cancer were retrospectively analyzed. Univariate and multivariate logistic regression analyses were performed to identify the predictors of DVT before surgery. Perioperative management of patients with DVTs and the incidence of postoperative PTE were investigated. Results: Of the total 1140 patients, 86 had DVT preoperatively. On univariate analysis, the incidence of DVT was significantly higher with: female sex; age ≥80 years; PS ≥ 1 (vs. PS = 0); stage IV (vs. stages I-III); history of preoperative chemotherapy; and the presence of a central venous catheter (CVC). Multivariate logistic regression analysis demonstrated that sex, age ≥80 years, PS ≥ 1, history of preoperative chemotherapy, and the presence of CVC were significantly correlated with DVT before surgery. Postoperative PTE occurred in 2 patients with proximal DVT. No patients in whom DVT was not detected developed PTE. Conclusions: Female sex, older age, worse PS, the presence of CVC, and a history of preoperative chemotherapy were the independent risk factors for DVT. Routine lower-extremity venous ultrasonographic screening is useful for prevention of PTE because it can identify patients at high or low risk for PTE.
- Subjects
VENOUS thrombosis prevention; GASTROINTESTINAL cancer; ULTRASONIC imaging; CANCER chemotherapy; CENTRAL venous catheters; DISEASE prevalence; PATIENTS
- Publication
Gastric Cancer, 2017, Vol 20, Issue 5, p878
- ISSN
1436-3291
- Publication type
Article
- DOI
10.1007/s10120-016-0677-2