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- Title
Editorial: Combination Cytokine Blockade: The Way Forward in Therapy for Rheumatoid Arthritis?
- Authors
Taylor, Peter C.; Williams, Richard O.
- Abstract
The article discusses a study which examined the potential dual inhibition of interleukin-17 (IL-17) and tumor necrosis factor (TNF) to advance therapeutic outcomes in rheumatoid arthritis (RA). Topics discussed include the rational pairing of IL-17 and TNF for dual cytokine blockade, the effect of stimulating human synovial fibroblasts with TNF and IL-17 and blocking experiments with small interfering ribonucleic acid (RNA).
- Subjects
IMMUNE system physiology; INTERLEUKINS; RHEUMATOID arthritis; TUMOR necrosis factors; CHEMICAL inhibitors
- Publication
Arthritis & Rheumatology, 2015, Vol 67, Issue 1, p14
- ISSN
2326-5191
- Publication type
Article
- DOI
10.1002/art.38893