We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
儿童春季卡他性角结膜炎伴干眼状态与病情严重程度的相关性.
- Authors
曾晓波; 许江涛; 邓敏; 聂正翠; 袁蕊梦; 朱婷燕
- Abstract
Objective To evaluate the condition of dry eyes in children with vernal keratoconjunctivitis in spring,and to explore the clinical characteristics as well as correlation with the severity of the disease. Method& children who were diagnosed with VKC in outpatient department from January to June in 2015 were recruited as the observation group. The control group consisted of 65 normal children matched in age and sex. Dry eye questionnaire,slit-lamp examination, break-up time test (BUT), fluorescein staining (FL) and Lid-wiper staining of Lid-wiper epitheliopathy (LWE) were performed in both groups. Statistical analyses were used to assessing these data. Results (1)The dry eye symptom scores of children with vernal keratoconjunctivitis in spring were significantly higher than those of normal children ( Z = -8.589 P < 0.01). Photophobia ( 23.59%), foreign body sensation ( 18.08%), frequent blinking( 14.49%) and uncomfortable in windy conditions( 20.90%) are the most common symptoms in VKC children.(2)The score of slit-lamp examination in VKC children was significantly higher than that in the normal group(Z = -9.902,P < 0.01).(3)The BUT was significantly shorter in VKC children (7.06±3.51) than in normal children(13.34±4.82)(Z = -6.729 P < 0.01). FL score(1.82±1.69)was significantly higher than that of normal children(0.23±0.46)(Z = -6.355 P < 0.01). The score of LWE (1.03±1.00) was significantly higher than that of normal children ( 0.31±0.50)( Z = -4.463 P < 0.01). (4) For VKC children,the severity of dry eye symptoms is correlated with slit-lamp checking scores(r = 0.259 P < 0.05);FL scores are also correlated with slitlamp checking scores (r = 0.269 P < 0.05);these children's BUT scores are correlated with FL (r = -0.283 P < 0.05) and LWE ( r = -0.252 P < 0.05) scores; FL scores are correlated with LWE scores (r = 0.307 P < 0.05). Conclusion Dry eyes do exist in VKC children. The severity of dry eye is correlated with the severity of VKC inflammation. This study provides a basis for further study on pathophysiology of dry eye in VKC children,as well as a reason for the use of artificial tears in acute stage of VKC.
- Publication
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao, 2020, Vol 41, Issue 12, p89
- ISSN
2095-610X
- Publication type
Article
- DOI
10.12259/j.issn.2095-610X.S20201225