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- Title
Risk factors associated with diagnostic discrepancy of gastric indefinite neoplasia: Who need en bloc resection?
- Authors
Goo, Ja; Choi, Cheol; Kang, Dae; Kim, Hyung; Park, Su; Cho, Mong; Hwang, Sun; Lee, Si; Goo, Ja Jun; Choi, Cheol Woong; Kang, Dae Hwan; Kim, Hyung Wook; Park, Su Bum; Hwang, Sun Hwi; Lee, Si Hak
- Abstract
<bold>Background: </bold>Endoscopic forceps biopsy is insufficient for a definitive diagnosis of dysplastic lesions. It is difficult to decide clinical management of gastric indefinite neoplasia diagnosed by endoscopic forceps biopsy when early gastric cancer (EGC) is macroscopically suspected. The aim of this study was to discuss the final results of gastric indefinite neoplasia and associated clinical factors predictive of early gastric cancer.<bold>Methods: </bold>The medical records of 119 patients who were diagnosed with gastric indefinite neoplasia by index forceps biopsy were retrospectively reviewed. The initial endoscopic findings were analyzed, and predictive factors of EGC were evaluated.<bold>Results: </bold>The final pathologic diagnoses of 119 patients included early gastric cancer (n = 26, 21.8%), adenoma (n = 6, 5.0%) and non-neoplasm (n = 87, 73.1%). Univariate analysis showed that lesion size greater than 10 mm, surface nodularity and surface redness were associated risk factors. In the multivariate analysis, lesions diameter (p = 0.021, OR 11.401, 95% CI 1.432-90.759) and surface redness (p = 0.014, OR 3.777, 95% CI 1.306-10.923) were significant risk factors.<bold>Conclusions: </bold>Patients with gastric indefinite neoplasia with larger size (≥10 mm) and surface redness might need further diagnostic investigation rather than simple follow-up endoscopy.
- Subjects
BIOPSY; CANCER diagnosis; STOMACH cancer; UNIVARIATE analysis; ENDOSCOPY; DYSPLASIA; DIAGNOSIS
- Publication
Surgical Endoscopy & Other Interventional Techniques, 2015, Vol 29, Issue 12, p3761
- ISSN
1866-6817
- Publication type
journal article
- DOI
10.1007/s00464-015-4151-8