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- Title
Evaluation of daptomycin susceptibility testing by Etest and the effect of different batches of media.
- Authors
Fuchs, Peter C.; Barry, Arthur L.; Brown, Steven D.; Fuchs, P C; Barry, A L; Brown, S D
- Abstract
One hundred and ninety-five Gram-positive bacteria representing 17 species were tested for susceptibility to daptomycin by broth microdilution and Etest methods. The geometric mean daptomycin MIC was 0.46 mg/L by broth microdilution tests and 0.73 mg/L by Etest. The concentration of calcium in 12 different batches of agar varied from 4 to 36 mg/L. Daptomycin Etest MICs varied inversely with the calcium concentration. Etest daptomycin MICs for quality control strains were within proposed quality control range on media with >20 mg/L of calcium. Monitoring the calcium levels of agar media by testing appropriate quality control strains is important for daptomycin Etests.
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 2001, Vol 48, Issue 4, p557
- ISSN
0305-7453
- Publication type
journal article
- DOI
10.1093/jac/48.4.557