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- Title
Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging.
- Authors
Yu, Seungjin; Choi, Goeun; Choy, Jin-Ho
- Abstract
Two-dimensional nanomaterials, particularly layered double hydroxides (LDHs), have been widely applied in the biomedical field owing to their biocompatibility, biodegradability, controllable drug release/loading ability, and enhanced cellular permeability. Since the first study analyzing intercalative LDHs in 1999, numerous studies have investigated their biomedical applications, including drug delivery and imaging; recent research has focused on the design and development of multifunctional LDHs. This review summarizes the synthetic strategies and in-vivo and in-vitro therapeutic actions and targeting properties of single-function LDH-based nanohybrids and recently reported (from 2019 to 2023) multifunctional systems developed for drug delivery and/or bio-imaging.
- Subjects
LAYERED double hydroxides; DRUG delivery systems; HYDROXIDES
- Publication
Nanomaterials (2079-4991), 2023, Vol 13, Issue 6, p1102
- ISSN
2079-4991
- Publication type
Article
- DOI
10.3390/nano13061102