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- Title
CRISPR: a new method for genetic engineering - A prokaryotic immune component may potentially open a new era of gene silencing.
- Authors
Amelio, I; Melino, G
- Abstract
The article focuses on the adaption of the Clustered, Regularly Interspaced, Short Palindromic Repeats (CRISPR), the prokaryotic immunity component that achieves genome engineering in mammalian cells. It is predicted that CRISPR can lead to a new paradigm of gene silencing. It is expected that its time-efficiency and cost-efficiency will strengthen its diffusion across agriculture, medicine and basic science.
- Subjects
IMMUNOGENETICS; IMMUNOREGULATION; IMMUNOGLOBULIN genetics; PROKARYOTIC genomes; GENE silencing; GENETIC engineering research
- Publication
Cell Death & Differentiation, 2015, Vol 22, Issue 1, p3
- ISSN
1350-9047
- Publication type
Article
- DOI
10.1038/cdd.2014.39