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- Title
Bisphosphonate safety and efficacy in chronic kidney disease.
- Authors
Ott, Susan M
- Abstract
A new population-based study of elderly patients hospitalized for a fracture and treated with an oral bisphosphonate finds no increased risk of acute kidney injury. The safety and efficacy of bisphosphonates may be different in patients with chronic kidney disease (CKD). The effects on vascular calcifications need further study, because low bone turnover might exacerbate vascular calcifications in patients with CKD. Even if bisphosphonates prove safe, their efficacy in this population is uncertain.
- Subjects
KIDNEY diseases; DIPHOSPHONATES; BONE fractures; CALCIFICATION; BONE diseases
- Publication
Kidney International, 2012, Vol 82, Issue 8, p833
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1038/ki.2012.253