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- Title
Psychological and Behavioural Impact of Genetic Testing Smokers for Lung Cancer Risk: A Phase II Exploratory Trial.
- Authors
Sanderson, Saskia C.; Humphries, Steve E.; Hubbart, Christina; Hughes, Eluned; Jarvis, Martin J.; Wardle, Jane
- Abstract
The behavioural and psychological impact of genetic testing for lung cancer susceptibility was examined among smokers (N = 61) who were randomly allocated to a GSTM1 genetic testing group (with GSTM1 - missing or GSTM1-present result) or no-test control group. The GSTM1-missing (higher risk) group reported greater motivation to quit smoking, and both genetic testing groups reported lower depression than the control group at one-week follow-up (p < .05 for all). Differences were not significant at two months follow-up. This study indicates the feasibility of much-needed research into the risks and benefits for individuals of emerging lifestyle-related genetic susceptibility tests.
- Subjects
SMOKING cessation; SMOKING &; psychology; LUNG cancer risk factors; HUMAN chromosome abnormality diagnosis; FEASIBILITY studies; DISEASE susceptibility
- Publication
Journal of Health Psychology, 2008, Vol 13, Issue 4, p481
- ISSN
1359-1053
- Publication type
Article
- DOI
10.1177/1359105308088519