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- Title
Effect of 4-hydroxychalcone as preventive and curative treatment in Wistar rats with liver injury.
- Authors
Acosta-Cota, Selene de Jesús; Castillo-Romero, Diego de Jesús; Montes-Ávila, Julio; Delgado-Vargas, Francisco; Báez-Flores, María Elena; Noguera-Corona, Elvic; Osuna-Martínez, Ulises
- Abstract
The article reviews the study which was conducted to determine the effect of 4-hydroxychalcone (4-HC) as preventive and curative treatment in acute and chronic liver injury, respectively in Wistar rats. the pre-treatment with 4-HC decreased transaminases, IL-6 serum levels, and hepatic malondialdehyde, increased IL-10 serum levels and hepatic glutathione and decreased liver damage. treatment with 4-HC after the induction of chronic liver injury decreased IL-6 serum levels and liver damage.
- Publication
Canadian Journal of Physiology & Pharmacology, 2022, Vol 100, Issue 10, p1005
- ISSN
0008-4212
- Publication type
Article
- DOI
10.1139/cjpp-2021-0628