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- Title
A case of lineage switch from B-cell acute lymphoblastic leukaemia to acute myeloid leukaemia. Role of subclonal/clonal gene mutations.
- Authors
Della Starza, Irene; Ceglie, Giulia; Nunes, Vittorio; Gianfelici, Valentina; Marinelli, Marilisa; Fuligni, Fabio; De Novi, Lucia Anna; De Propris, Maria Stefania; Vitale, Antonella; Chiaretti, Sabina; Guarini, Anna; Foà, Robin
- Abstract
The article describes the case of a 40-year-old white female patient with a history of auxiliary lymphadenopathy and who developed acute lymphoblastic leukemia (ALL) with myeloid phenotype at relapse. The diagnosis was confirmed after performing peripheral blood cell count, peripheral blood smear morphology and real-time quantitative polymerase chain reaction (RQ-PCR). The patient was subjected to chemotherapy and given clofarabine and cytarabine.
- Subjects
CYTARABINE
- Publication
British Journal of Haematology, 2016, Vol 174, Issue 4, p648
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1111/bjh.13800