We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Serum 25-hydroxyvitamin D and elderly skeletal muscle mass and function in urban north China.
- Authors
Liping Meng; Qingqing Man; Linhong Yuan; Lingxia Shen; Weimin Li; Guiyuan Guo; Lixiang Li; Shanshan Jia; Yixiong Gao; Pengkun Song; Jian Zhang; Meng, Liping; Man, Qingqing; Yuan, Linhong; Shen, Lingxia; Li, Weimin; Guo, Guiyuan; Li, Lixiang; Jia, Shanshan; Gao, Yixiong
- Abstract
<bold>Background and Objectives: </bold>To investigate the association of serum 25-hydroxyvitamin D (25(OH)D) with skeletal muscle mass (SMM) and function among the elderly in an urban area in northern China.<bold>Methods and Study Design: </bold>A total of 912 participants (316 men, 596 women) aged more than 60 years from 4 communities in Beijing were enrolled. Serum concentrations of 25(OH)D were measured through radioimmunoassay. SMM was assessed through bioelectrical impendence analysis, whereas skeletal muscle function was assessed through grip strength and 4-m regular gait speed measurements. On the basis of expert consensus of the Asian Working Group for Sarcopenia, low muscle mass was defined as relative skeletal mass index (RSMI) <7.0 kg/m2 for men and <5.7 kg/m2 for women. A noncondition logistical regression model was employed to explore the association between vitamin D and both muscle mass and function.<bold>Results: </bold>Serum 25(OH)D was positively associated with grip strength (β=0.16, SE=0.05). The upper quartile of 25(OH)D was negatively associated with loss of grip strength (OR=0.05, 95% CI: 0.01-0.48) in men but not in women. No significant associations were noted between 25(OH)D and appendicular skeletal muscle mass, RSMI, and gait speed.<bold>Conclusions: </bold>The present study demonstrated a positive association between vitamin D and skeletal muscle strength in elderly Chinese men but not women.
- Subjects
CHINA; SERUM; VITAMIN D; SKELETAL muscle; OLDER people; BLOOD plasma; MUSCULAR atrophy; MUSCLE growth; RADIOIMMUNOASSAY; BODY composition; SKELETAL muscle physiology; GRIP strength; BIOELECTRIC impedance; METROPOLITAN areas; SEX distribution; LOGISTIC regression analysis; OLD age
- Publication
Asia Pacific Journal of Clinical Nutrition, 2017, Vol 26, Issue 5, p849
- ISSN
0964-7058
- Publication type
journal article
- DOI
10.6133/apjcn.072016.13