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- Title
Prevention of Rectal SHIV Transmission in Macaques by Daily or Intermittent Prophylaxis with Emtricitabine and Tenofovir.
- Authors
García-Lerma, J. Gerardo; Otten, Ron A; Qari, Shoukat H; Jackson, Eddie; Cong51, Mian-er; Masciotra, Silvina; Wei Luo; Kim, Caryn; Adams, Debra R; Monsour, Michael; Lipscomb, Jonathan; Johnson, Jeffrey A.; Delinsky, David; Schinazi, Raymond F.; Janssen, Robert; Folks, Thomas M.; Heneine, Walid
- Abstract
Using a repeat-exposure macaque model, Walid Heneine and colleagues find that pre-exposure prophylaxis with combination antiretroviral drugs provides protection against rectal challenge with a SHIV virus.
- Subjects
ANTIRETROVIRAL agents; HIV infections; HIV; MACAQUES; HENEINE, Walid
- Publication
PLoS Medicine, 2008, Vol 5, Issue 2, pe28
- ISSN
1549-1277
- Publication type
Article
- DOI
10.1371/journal.pmed.0050028