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- Title
A case of azoospermia in a bull carrying a Y-autosome reciprocal translocation.
- Authors
Iannuzzi, L.; Molteni, L.; Di Meo, G. P.; de Giovanni, A.; Perucatti, A.; Succi, G.; Incarnato, D.; Eggen, A.; Cribiu, E. P.
- Abstract
During normal cytogenetic investigations on the Chianina cattle (BTA) breed, a normal looking young bull was found to carry an abnormal Y chromosome which was a product of a reciprocal translocation between chromosomes Y and 9. This was revealed by both CBA- and RBG-banding techniques and was clearly confirmed by FISH-mapping analysis with IDVGA50 (which paints the complete Yq arm in a normal Y), as well as with AMD1, CGA, IGF2R (mapping to BTA9q16, BTA9q22 and BTA9q27→q28, respectively) and SRY (mapping to normal BTAYq23). Analysis on sperm from four different samples revealed azoospermia in the carrier, indicating that the rcp(Y;9) induces sterility in the bull. Copyright © 2002 S. Karger AG, Basel
- Subjects
CHROMOSOMAL translocation; Y chromosome; GENE mapping; INFERTILITY; CHIANA cattle; FLUORESCENCE in situ hybridization
- Publication
Cytogenetics & Cell Genetics, 2001, Vol 95, Issue 3/4, p225
- ISSN
0301-0171
- Publication type
Article
- DOI
10.1159/000059349