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- Title
Transgenic mice expressing mutant caveolin-3 show severe myopathy associated with increased nNOS activity.
- Authors
Sunada, Yoshihide
- Abstract
Examines transgenic mice expressing the Pro104Leu mutant caveolin-3, the muscle-specific isoform of the caveolin protein family. Interaction of caveolin-3 with neuronal nitric oxide synthase (nNOS); Presence of severe myopathy in sarcolemma; Activity of nNOS in skeletal muscle.
- Subjects
TRANSGENIC mice; GENETIC mutation; NITRIC-oxide synthases; GENETICS
- Publication
Human Molecular Genetics, 2001, Vol 10, Issue 3, p173
- ISSN
0964-6906
- Publication type
Article
- DOI
10.1093/hmg/10.3.173