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- Title
A catalogue of imprinted genes and parent-of-origin effects in humans and animals.
- Authors
Morison, Ian M.; Reeve, Anthony E.
- Abstract
Parent-of-origin effects were first recorded >3000 years ago by mule breeders in Asia Minor. There are now several different types of evidence suggesting the presence of a large number of imprinted genes, many of which have not yet been identified. Here, we catalogue a wide range of evidence and phenomena which indicate or suggest the presence of genomic imprinting in animals. This evidence includes: the direct documentation of parent-of-origin-specific gene transcription; human disease inheritance patterns which suggest the involvement of imprinted genes; and older, less well studied animal models which may show parent-of-origin effects.
- Subjects
MULES; GENOMIC imprinting; GENETIC transcription; BREEDING
- Publication
Human Molecular Genetics, 1998, Vol 7, Issue 10, p1599
- ISSN
0964-6906
- Publication type
Article
- DOI
10.1093/hmg/7.10.1599