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- Title
A New Lanostanoid from Ganoderma lucidum.
- Authors
Li, Peng; Shen, Cui-E; Nan, Ting-Ting; Xu, Jian-Hua
- Abstract
Phytochemical studies on the ethyl acetate extract of the fruiting body of Ganoderma lucidum afforded a new lanostanoid named 24(S),26-dihydroxy-5 α-lanosta-7,9,25-trien-3-one ( 1), along with two known compounds, ganoderic acid DM ( 2) and 5 α-lanosta-7,9(11),24-triene-15 α,26-dihydroxy-3-one ( 3). Their structures were established on the basis of spectroscopic analysis and chemical evidence. The cytotoxicity of the isolated compounds was evaluated in vitro against three human cancer cell lines (HCT-116, KB, and OE-19). Compound 3 showed moderate cytotoxic activity.
- Subjects
ETHYL acetate; GANODERMA lucidum; LANOSTANOIDS; SPECTRUM analysis; CELL lines
- Publication
Chemistry of Natural Compounds, 2016, Vol 52, Issue 1, p71
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-016-1549-z