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- Title
Potomac horse fever in Ontario: Clinical, geographic, and diagnostic aspects.
- Authors
Arroyo, Luis G.; Moore, Alison; Bedford, Sofia; Gomez, Diego E.; Teymournejad, Omid; Xiong, Qingming; Budachetri, Khemraj; Bekebrede, Hannah; Rikihisa, Yasuko; Baird, John D.
- Abstract
Clinical findings, geographic locations, laboratory diagnoses, and culture isolation of Neorickettsia spp. in Potomac horse fever (PHF) cases diagnosed in Ontario between 2015 and 2019 are described. Forty-six confirmed PHF cases occurred from late June to early September. Of 41 horses admitted to the Ontario Veterinary College, 28 (68%) survived and 13 (32%) were euthanized due to poor prognosis or financial constraints. Most cases were in southern Ontario along the Canada-USA border. Blood and fecal samples from 43 suspect PHF cases were submitted to 2 laboratories for polymerase chain reaction (PCR) testing for Neorickettsia risticii. Agreement between both laboratories for detection of N. risticii DNA was excellent for feces [k = 0.932, 95% confidence interval (CI): 0.80 to 1], and fair for blood samples (k = 0.494, 95% CI: 0.13 to 0.85). Neorickettia spp. were isolated from 16 of 41 (39%) blood samples. DNA analysis confirmed 14 isolates were N. risticii and 2 were N. findlayensis, a novel species of Neorickettsia recently demonstrated to cause PHF.
- Subjects
ONTARIO; CANADA; DNA analysis; POLYMERASE chain reaction; CLINICAL pathology; HORSES; FEVER
- Publication
Canadian Veterinary Journal / Revue Vétérinaire Canadienne, 2021, Vol 62, Issue 6, p622
- ISSN
0008-5286
- Publication type
Article