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- Title
Proteína C-reactiva ultrasensible, estado nutricional y perfil bioquímico en escolares mexicanos.
- Authors
Haro-Acosta, María Elena; Esparza-Cisneros, Josefina Ruíz; Delgado-Valdez, Jesús Hernán; Ayala-Figuero, Rafael Iván
- Abstract
Background: C-reactive protein (CRP)isa nonspecific marker of inflammation with low serum levels, which are not usually detectable. In order to assess cardiovascular risk in adults apparently healthy, ultrasensitive methods are used, and the CRP measured through these techniques is known as ultrasensitive C-reactive protein (US-CRP). Some researchers report an association of US-CRP with some anthropometric parameters in children with no apparent disease. The aim was to associate US-CRP with nutritional status and biochemical profiles in Mexican schoolchildren. Methods: In this cross-sectional study 300 healthy children (aged 10 to 12 years) were evaluated. Weight, height, body mass index (BMI), waist circumference, body fat percentage, glucose, lipid profiles and US-CRP were measured. Exclusion criteria was: US-CRP > 10mg/L. We used multivariate regression models. Results: 53.7 % were girls and 46.3 % were boys. The US-CRP median was of 0.3 mg/L (range: 0.3 mg/L-6.8 mg/L), and it was positively and significantly correlated with BMI (β = 0.226, p = 0.032) and LDL-C (β = -0.267, p = 0.007) and negatively associated with cholesterol (β = -0.267, p = 0.007). Conclusion: There is an association between US-CRP and cardiovascular risk indicators, such as obesity and some lipid disorder in childhood; therefore, US-CRP may be used for close examination in Mexican children.
- Subjects
CARDIOVASCULAR diseases risk factors; C-reactive protein; ACUTE phase proteins; CHILDREN'S health; HEALTH of school children; NUTRITIONAL status; CHILD nutrition; BODY mass index
- Publication
Revista Medica del IMSS, 2014, Vol 52, Issue 4, p398
- ISSN
0443-5117
- Publication type
Article