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- Title
Atrial Fibrillation Is Associated With Increased Mean Platelet Volume and Apnea Hypopnea Index in Patients With Obstructive Sleep Apnea.
- Authors
Akyüz, Aydın; Akkoyun, Dursun Çayan; Değirmenci, Hasan; Alp, Recep
- Abstract
This study investigated whether there is a relationship between atrial fibrillation (AF), mean platelet volume (MPV), and apnea hypopnea index (AHI) in patients who have obstructive sleep apnea syndrome (OSAS). We enrolled patients who had OSAS with either AF or normal sinus rhythm (NSR). We divided 90 patients (aged 50-80 years) into 2 groups: group 1 consisted of 40 patients with OSAS having AF and group 2 of 50 patients with OSAS having NSR. Mean platelet volume was higher in patients with AF than in those with NSR (9.8 ± 0.6 vs 8.4 ± 0.6 fL; P < .001). The MPV and AHI were substantial variables associated with AF (odds ratio [OR] = 2.41; 95% confidence interval [CI], 1.36-5.26; P < .004 and OR = 1.91; 95% CI, 1.26-3.32; P = .02). Elevated MPV value of ≥9.4 fL is associated with AF (70% sensitivity and 63% specificity). More research is needed to establish the clinical relevance of this association.
- Subjects
ATRIAL fibrillation; CONFIDENCE intervals; SLEEP apnea syndromes; STATISTICS; T-test (Statistics); LOGISTIC regression analysis; POLYSOMNOGRAPHY; DATA analysis; RETROSPECTIVE studies; RECEIVER operating characteristic curves; LABORATORY test panels; DATA analysis software; DESCRIPTIVE statistics; MEAN platelet volume; ODDS ratio; MANN Whitney U Test
- Publication
Angiology, 2015, Vol 66, Issue 6, p525
- ISSN
0003-3197
- Publication type
Article
- DOI
10.1177/0003319714548567