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- Title
Two Surface Activation Strategies to Functionalize Cotton Fibers with Cys-LC-LL-37 Antibacterial Peptide.
- Authors
Mouro, Cláudia; Pedrosa, Marta; Vaz, Joana; Gouveia, Isabel
- Abstract
his investigation aimed to determine which of two surface activation methods, N,N-carbonyldiimidazole (CDI) or 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO), allowed more effective bonding of Cys-LC-LL-37, an antimicrobial peptide (AMP), onto cotton fibers and which one presented greater antimicrobial activity. he antibacterial effect of the TEMPO-activated cotton functionalized with this AMP was more effective against Staphylococcus aureus, while the effect of this AMP covalently bonded onto cotton fibers was more effective against Klebsiella pneumoniae. CDI-activated cotton retained a higher percentage of the AMP, making this bioactive strategy the choice for development of AMP antimicrobial textiles.
- Subjects
COTTON fibers; PLANT fibers; PEPTIDES; PROTEINS; ANTIBACTERIAL agents
- Publication
AATCC Review, 2014, p47
- ISSN
1532-8813
- Publication type
Article
- DOI
10.14504/ajr.1.6.4