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- Title
Dehydroepiandrosterone sulfate in postmenopausal women: lack of influence of parity.
- Authors
Carlström, Kjell; Lagrelius, Anders; Lunell, Nils-Olov; Möllerström, Gunnar; Rannevik, Gunnar; von Schoultz, Bo; Carlström, K; Lagrelius, A; Lunell, N O; Möllerström, G; Rannevik, G; von Schoultz, B
- Abstract
Serum concentrations of dehydroepiandrosterone sulfate (DHAS) were analyzed in 251 healthy, medicine-free postmenopausal women 46-65 years of age. Twentyfour of the women were nulliparous and 227 parous (1- to 7-parous). There was no association, whatsoever, between parity and DHAS levels. The data are at variance with previous findings in menstruating women of higher DHAS levels in nulliparous than in parous women. This difference between menstruating and postmenopausal women may reflect an influence of age per se on DHAS metabolism. It may also reflect the exclusion in this study of women with i.e. endometrial hyperplasia/cancer, diseases often associated with elevated DHAS levels and increased risk for nulliparous women.
- Publication
Gynecologic & Obstetric Investigation, 1989, Vol 28, Issue 1, p35
- ISSN
0378-7346
- Publication type
journal article
- DOI
10.1159/000293498