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- Title
Safe sedation management using volatile anesthetics during cardiopulmonary bypass.
- Authors
Tamura, Takahiro; Mori, Atsushi; Nishiwaki, Kimitoshi
- Abstract
Several pieces of evidence suggest that volatile anesthetics (VAs), which were originally used as sedatives, have myocardial protective effects against cardiac ischemia–reperfusion injury. In Europe and the United States, the use of VAs during cardiopulmonary bypass (CPB) is widespread, as 2019 European Association for Cardio-Thoracic Surgery (EACTS)/European Association of Cardiothoracic Anaesthesiology/European Board of Cardiovascular Perfusion, 2011 American College of Cardiology/American Heart Association, and 2017 EACTS guidelines recommend their use in cardiovascular surgery, based on their potential myocardial protective effects. In other countries, including Japan, the use of VAs is gradually increasing. Therefore, it is important to be aware of the risks and possible adverse events associated with VA use during CPB to ensure safe sedation management. Herein, we describe in detail issues such as intraoperative awareness, air pollution, and damage to oxygenators due to VA use and propose precautions.
- Subjects
CARDIOPULMONARY bypass; CARDIOVASCULAR surgery; INTRAOPERATIVE awareness; ANESTHETICS; AMERICAN College of Cardiology; AMERICAN Heart Association; OXYGENATORS; REPERFUSION injury
- Publication
Journal of Anesthesia, 2022, Vol 36, Issue 2, p287
- ISSN
0913-8668
- Publication type
Article
- DOI
10.1007/s00540-022-03054-7