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Budget impact analysis of extended half-life recombinant factor IX (rFIXFc) in the treatment of haemophilia B.
Published in:
Global & Regional Health Technology Assessment, 2020, v. 7, n. 1, p. 40, doi. 10.33393/grhta.2020.2113
By:
- Aiello, Andrea;
- Mancuso, Maria E.;
- Colombo, Alessio;
- Teruzzi, Cristina;
- Berto, Patrizia
Publication type:
Article
JNK Plays a Key Role in Tau Hyperphosphorylation in Alzheimer's Disease Models.
Published in:
Journal of Alzheimer's Disease, 2011, v. 26, n. 2, p. 315, doi. 10.3233/JAD-2011-110320
By:
- Ploia, Cristina;
- Antoniou, Xanthi;
- Sclip, Alessandra;
- Grande, Valentina;
- Cardinetti, Daniele;
- Colombo, Alessio;
- Canu, Nadia;
- Benussi, Luisa;
- Ghidoni, Roberta;
- Forloni, Gianluigi;
- Borsello, Tiziana
Publication type:
Article
Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism.
Published in:
EMBO Molecular Medicine, 2019, v. 11, n. 6, p. N.PAG, doi. 10.15252/emmm.201809711
By:
- Götzl, Julia K;
- Brendel, Matthias;
- Werner, Georg;
- Parhizkar, Samira;
- Sebastian Monasor, Laura;
- Kleinberger, Gernot;
- Colombo, Alessio‐Vittorio;
- Deussing, Maximilian;
- Wagner, Matias;
- Winkelmann, Juliane;
- Diehl‐Schmid, Janine;
- Levin, Johannes;
- Fellerer, Katrin;
- Reifschneider, Anika;
- Bultmann, Sebastian;
- Bartenstein, Peter;
- Rominger, Axel;
- Tahirovic, Sabina;
- Smith, Scott T;
- Madore, Charlotte
Publication type:
Article
Human stem cell–derived monocytes and microglia‐like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, n. 3, p. 453, doi. 10.1016/j.jalz.2018.09.006
By:
- Claes, Christel;
- Van Den Daele, Johanna;
- Boon, Ruben;
- Schouteden, Sarah;
- Colombo, Alessio;
- Monasor, Laura Sebastian;
- Fiers, Mark;
- Ordovás, Laura;
- Nami, FatemehArefeh;
- Bohrmann, Bernd;
- Tahirovic, Sabina;
- De Strooper, Bart;
- Verfaillie, Catherine M.
Publication type:
Article
Impaired Retromer Function in Niemann-Pick Type C Disease Is Dependent on Intracellular Cholesterol Accumulation.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13256, doi. 10.3390/ijms222413256
By:
- Dominko, Kristina;
- Rastija, Ana;
- Sobocanec, Sandra;
- Vidatic, Lea;
- Meglaj, Sarah;
- Lovincic Babic, Andrea;
- Hutter-Paier, Birgit;
- Colombo, Alessio-Vittorio;
- Lichtenthaler, Stefan F.;
- Tahirovic, Sabina;
- Hecimovic, Silva
Publication type:
Article
In vivo Ca<sup>2+</sup> imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria.
Published in:
Glia, 2019, v. 67, n. 5, p. 985, doi. 10.1002/glia.23584
By:
- Montagna, Elena;
- Crux, Sophie;
- Luckner, Manja;
- Herber, Julia;
- Colombo, Alessio V.;
- Marinković, Petar;
- Tahirovic, Sabina;
- Lichtenthaler, Stefan F.;
- Wanner, Gerhard;
- Müller, Ulrike C.;
- Sgobio, Carmelo;
- Herms, Jochen
Publication type:
Article
Microbiota-derived short chain fatty acids modulate microglia and promote Ab plaque deposition.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.59826
By:
- Colombo, Alessio Vittorio;
- Sadler, Rebecca Katie;
- Llovera, Gemma;
- Singh, Vikramjeet;
- Roth, Stefan;
- Heindl, Steffanie;
- Monasor, Laura Sebastian;
- Verhoeven, Aswin;
- Peters, Finn;
- Parhizkar, Samira;
- Kamp, Frits;
- Gomez de Aguero, Mercedes;
- MacPherson, Andrew J.;
- Winkler, Edith;
- Herms, Jochen;
- Benakis, Corinne;
- Dichgans, Martin;
- Steiner, Harald;
- Giera, Martin;
- Haass, Christian
Publication type:
Article
Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.12748
By:
- Kuhn, Peer-Hendrik;
- Colombo, Alessio Vittorio;
- Schusser, Benjamin;
- Dreymueller, Daniela;
- Wetzel, Sebastian;
- Schepers, Ute;
- Herber, Julia;
- Ludwig, Andreas;
- Kremmer, Elisabeth;
- Montag, Dirk;
- Müller, Ulrike;
- Schweizer, Michaela;
- Saftig, Paul;
- Bräse, Stefan;
- Lichtenthaler, Stefan F.
Publication type:
Article
Emergence of Carbapenem-Resistant Klebsiella pneumoniae: Progressive Spread and Four-Year Period of Observation in a Cardiac Surgery Division.
Published in:
BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/871947
By:
- Lombardi, Fortunata;
- Gaia, Paola;
- Valaperta, Rea;
- Cornetta, Maria;
- Tejada, Milvana Rosa;
- Di Girolamo, Luca;
- Moroni, Alessandra;
- Ramundo, Federica;
- Colombo, Alessio;
- Valisi, Massimiliano;
- Costa, Elena
Publication type:
Article
From back-analysis to run-out prediction: a case study in the Western Italian Alps.
Published in:
Landslides, 2011, v. 8, n. 2, p. 159, doi. 10.1007/s10346-010-0248-2
By:
- Pirulli, Marina;
- Colombo, Alessio;
- Scavia, Claudio
Publication type:
Article
Therapeutic potential of BACE1/beta-secretase: Proteome-wide identification of physiological BACE1 substrates in primary neurons and mouse brain
Published in:
2012
By:
- Lichtenthaler, Stefan;
- Dislich, Bastian;
- Hogl, Sebastian;
- Colombo, Alessio;
- Zeitschel, Ulrike;
- Willem, Michael;
- Haass, Christian;
- Volbracht, Christiane;
- Roßner, Steffen;
- Kuhn, Peer-Hendrik
Publication type:
Abstract
P1-428: Phosphorylation of APP, TAU and PIN1 is regulated by JNK
Published in:
2008
By:
- Forloni, Gianluigi;
- Colombo, Alessio;
- Borsello, Tiziana
Publication type:
Abstract
P4-053: JNK regulates APP processing
Published in:
2006
By:
- Colombo, Alessio;
- Santambrogio, Sara;
- Repici, Mariaelena;
- Centeno, Catherine;
- Ploia, Cristina;
- Forloni, Gianluigi;
- Borsello, Tiziana
Publication type:
Abstract
P4-053: JNK regulates APP processing
Published in:
2006
By:
- Colombo, Alessio;
- Santambrogio, Sara;
- Repici, Mariaelena;
- Centeno, Catherine;
- Ploia, Cristina;
- Forloni, Gianluigi;
- Borsello, Tiziana
Publication type:
Abstract
Determination of the Proteolytic Cleavage Sites of the Amyloid Precursor-Like Protein 2 by the Proteases ADAM10, BACE1 and &ggr;-Secretase.
Published in:
PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021337
By:
- Hogl, Sebastian;
- Kuhn, Peer-Hendrik;
- Colombo, Alessio;
- Lichtenthaler, Stefan F.
Publication type:
Article
Phenotypic correlates of serum neurofilament light chain levels in amyotrophic lateral sclerosis.
Published in:
Frontiers in Aging Neuroscience, 2023, v. 15, p. 1, doi. 10.3389/fnagi.2023.1132808
By:
- Verde, Federico;
- Milone, Ilaria;
- Maranzano, Eleonora Colombo Alessio;
- Solca, Federica;
- Torre, Silvia;
- Doretti, Alberto;
- Gentile, Francesco;
- Manini, Arianna;
- Bonetti, Ruggero;
- Peverelli, Silvia;
- Messina, Stefano;
- Maderna, Luca;
- Morelli, Claudia;
- Poletti, Barbara;
- Ratti, Antonia;
- Silani, Vincenzo;
- Ticozzi, Nicola
Publication type:
Article
Neurotoxic and Gliotrophic Activity of a Synthetic Peptide Homologous to Gerstmann-Sträussler-Scheinker Disease Amyloid Protein.
Published in:
Journal of Neuroscience, 2007, v. 27, n. 7, p. 1576, doi. 10.1523/JNEUROSCI.5145-06.2007
By:
- Fioriti, Luana;
- Angeretti, Nadia;
- Colombo, Laura;
- De Luigi, Ada;
- Colombo, Alessio;
- Manzoni, Claudia;
- Morbin, Michela;
- Tagliavini, Fabrizio;
- Salmona, Mario;
- Chiesa, Roberto;
- Forloni, Gianluigi
Publication type:
Article
Non‐cell‐autonomous function of DR6 in Schwann cell proliferation.
Published in:
EMBO Journal, 2018, v. 37, n. 7, p. 1, doi. 10.15252/embj.201797390
By:
- Colombo, Alessio;
- Hsia, Hung‐En;
- Wang, Mengzhe;
- Kuhn, Peer‐Hendrik;
- Brill, Monika S.;
- Canevazzi, Paolo;
- Feederle, Regina;
- Taveggia, Carla;
- Misgeld, Thomas;
- Lichtenthaler, Stefan F.
Publication type:
Article
Young microglia restore amyloid plaque clearance of aged microglia.
Published in:
EMBO Journal, 2017, v. 36, n. 5, p. 583, doi. 10.15252/embj.201694591
By:
- Daria, Anna;
- Colombo, Alessio;
- Llovera, Gemma;
- Hampel, Heike;
- Willem, Michael;
- Liesz, Arthur;
- Haass, Christian;
- Tahirovic, Sabina
Publication type:
Article
TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons.
Published in:
EMBO Journal, 2016, v. 35, n. 21, p. 2350, doi. 10.15252/embj.201694221
By:
- Schwenk, Benjamin M;
- Hartmann, Hannelore;
- Serdaroglu, Alperen;
- Schludi, Martin H;
- Hornburg, Daniel;
- Meissner, Felix;
- Orozco, Denise;
- Colombo, Alessio;
- Tahirovic, Sabina;
- Michaelsen, Meike;
- Schreiber, Franziska;
- Haupt, Simone;
- Peitz, Michael;
- Brüstle, Oliver;
- Küpper, Clemens;
- Klopstock, Thomas;
- Otto, Markus;
- Ludolph, Albert C;
- Arzberger, Thomas;
- Kuhn, Peer‐Hendrik
Publication type:
Article
Shedding of glycan-modifying enzymes by signal peptide peptidase-like 3 ( SPPL3) regulates cellular N-glycosylation.
Published in:
EMBO Journal, 2014, v. 33, n. 24, p. 2890, doi. 10.15252/embj.201488375
By:
- Voss, Matthias;
- Künzel, Ulrike;
- Higel, Fabian;
- Kuhn, Peer‐Hendrik;
- Colombo, Alessio;
- Fukumori, Akio;
- Haug‐Kröper, Martina;
- Klier, Bärbel;
- Grammer, Gudula;
- Seidl, Andreas;
- Schröder, Bernd;
- Obst, Reinhard;
- Steiner, Harald;
- Lichtenthaler, Stefan F;
- Haass, Christian;
- Fluhrer, Regina
Publication type:
Article
Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons.
Published in:
EMBO Journal, 2012, v. 31, n. 14, p. 3157, doi. 10.1038/emboj.2012.173
By:
- Kuhn, Peer-Hendrik;
- Koroniak, Katarzyna;
- Hogl, Sebastian;
- Colombo, Alessio;
- Zeitschel, Ulrike;
- Willem, Michael;
- Volbracht, Christiane;
- Schepers, Ute;
- Imhof, Axel;
- Hoffmeister, Albrecht;
- Haass, Christian;
- Roßner, Steffen;
- Bräse, Stefan;
- Lichtenthaler, Stefan F
Publication type:
Article
ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons.
Published in:
EMBO Journal, 2010, v. 29, n. 17, p. 3020, doi. 10.1038/emboj.2010.167
By:
- Kuhn, Peer-Hendrik;
- Wang, Huanhuan;
- Dislich, Bastian;
- Colombo, Alessio;
- Zeitschel, Ulrike;
- Ellwart, Joachim W;
- Kremmer, Elisabeth;
- Roßner, Steffen;
- Lichtenthaler, Stefan F
Publication type:
Article
Evaluation of human gene variant detection in amplicon pools by the GS-FLX parallel Pyrosequencer.
Published in:
BMC Genomics, 2008, v. 9, p. 1, doi. 10.1186/1471-2164-9-464
By:
- Bordoni, Roberta;
- Bonnal, Raoul;
- Rizzi, Ermanno;
- Carrera, Paola;
- Benedetti, Sara;
- Cremonesi, Laura;
- Stenirri, Stefania;
- Colombo, Alessio;
- Montrasio, Cristina;
- Bonalumi, Sara;
- Albertini, Alberto;
- Bernardi, Luigi Rossi;
- Ferrari, Maurizio;
- De Bellis, Gianluca
Publication type:
Article
Blocking ADAM10 synaptic trafficking generates a model of sporadic Alzheimer’s disease.
Published in:
Brain: A Journal of Neurology, 2010, v. 133, n. 11, p. 3323, doi. 10.1093/brain/awq217
By:
- Epis, Roberta;
- Marcello, Elena;
- Gardoni, Fabrizio;
- Vastagh, Csaba;
- Malinverno, Matteo;
- Balducci, Claudia;
- Colombo, Alessio;
- Borroni, Barbara;
- Vara, Hugo;
- Dell'Agli, Mario;
- Cattabeni, Flamino;
- Giustetto, Maurizio;
- Borsello, Tiziana;
- Forloni, Gianluigi;
- Padovani, Alessandro;
- Luca, Monica Di
Publication type:
Article
Low-Cost GNSS Solution for Continuous Monitoring of Slope Instabilities Applied to Madonna Del Sasso Sanctuary (NW Italy).
Published in:
Sensors (14248220), 2020, v. 20, n. 1, p. 289, doi. 10.3390/s20010289
By:
- Notti, Davide;
- Cina, Alberto;
- Manzino, Ambrogio;
- Colombo, Alessio;
- Bendea, Iosif Horea;
- Mollo, Paolo;
- Giordan, Daniele
Publication type:
Article
Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer's disease.
Published in:
Cell Death & Disease, 2021, v. 12, n. 8, p. 1, doi. 10.1038/s41419-021-04062-3
By:
- Bettegazzi, Barbara;
- Sebastian Monasor, Laura;
- Bellani, Serena;
- Codazzi, Franca;
- Restelli, Lisa Michelle;
- Colombo, Alessio Vittorio;
- Deigendesch, Nikolaus;
- Frank, Stephan;
- Saito, Takashi;
- Saido, Takaomi C.;
- Lammich, Sven;
- Tahirovic, Sabina;
- Grohovaz, Fabio;
- Zacchetti, Daniele
Publication type:
Article
TI-VAMP/VAMP7 is the SNARE of secretory lysosomes contributing to ATP secretion from astrocytes.
Published in:
Biology of the Cell (Wiley-Blackwell), 2012, v. 104, n. 4, p. 213, doi. 10.1111/boc.201100070
By:
- Verderio, Claudia;
- Cagnoli, Cinzia;
- Bergami, Matteo;
- Francolini, Maura;
- Schenk, Ursula;
- Colombo, Alessio;
- Riganti, Loredana;
- Frassoni, Carolina;
- Zuccaro, Emanuela;
- Danglot, Lydia;
- Wilhelm, Claire;
- Galli, Thierry;
- Canossa, Marco;
- Matteoli, Michela
Publication type:
Article
JNK Contributes to Hif-1α Regulation in Hypoxic Neurons.
Published in:
Molecules, 2010, v. 15, n. 1, p. 114, doi. 10.3390/molecules15010114
By:
- Antoniou, Xanthi;
- Sclip, Alessandra;
- Ploia, Cristina;
- Colombo, Alessio;
- Moroy, Gautier;
- Borsello, Tiziana
Publication type:
Article
BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.
Published in:
PLoS ONE, 2018, p. 1, doi. 10.1371/journal.pone.0200344
By:
- Causevic, Mirsada;
- Dominko, Kristina;
- Malnar, Martina;
- Vidatic, Lea;
- Cermak, Stjepko;
- Pigoni, Martina;
- Kuhn, Peer-Hendrik;
- Colombo, Alessio;
- Havas, Daniel;
- Flunkert, Stefanie;
- McDonald, Jessica;
- Gunnersen, Jenny M.;
- Hutter-Paier, Birgit;
- Tahirovic, Sabina;
- Windisch, Manfred;
- Krainc, Dimitri;
- Lichtenthaler, Stefan F.;
- Hecimovic, Silva
Publication type:
Article
A role for P2X<sub>7</sub> in microglial proliferation.
Published in:
Journal of Neurochemistry, 2006, v. 99, n. 3, p. 745, doi. 10.1111/j.1471-4159.2006.04101.x
By:
- Bianco, Fabio;
- Ceruti, Stefania;
- Colombo, Alessio;
- Fumagalli, Marta;
- Ferrari, Davide;
- Pizzirani, Cinzia;
- Matteoli, Michela;
- Di Virgilio, Francesco;
- Abbracchio, Maria P.;
- Verderio, Claudia
Publication type:
Article
Identification and Characterization of DM1 Patients by a New Diagnostic Certified Assay: Neuromuscular and Cardiac Assessments.
Published in:
BioMed Research International, 2013, v. 2013, p. 1, doi. 10.1155/2013/958510
By:
- Valaperta, Rea;
- Sansone, Valeria;
- Lombardi, Fortunata;
- Verdelli, Chiara;
- Colombo, Alessio;
- Valisi, Massimiliano;
- Brigonzi, Elisa;
- Costa, Elena;
- Meola, Giovanni
Publication type:
Article
Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21428-5
By:
- Colombo, Alessio;
- Dinkel, Lina;
- Müller, Stephan A.;
- Sebastian Monasor, Laura;
- Schifferer, Martina;
- Cantuti-Castelvetri, Ludovico;
- König, Jasmin;
- Vidatic, Lea;
- Bremova-Ertl, Tatiana;
- Lieberman, Andrew P.;
- Hecimovic, Silva;
- Simons, Mikael;
- Lichtenthaler, Stefan F.;
- Strupp, Michael;
- Schneider, Susanne A.;
- Tahirovic, Sabina
Publication type:
Article
Molecular detection of SARS-CoV-2 eta VOI in Northern Italy: a case report.
Published in:
2022
By:
- Broccolo, Francesco;
- Giovanetti, Marta;
- Colombo, Alessio;
- Perrelli, Nicola;
- Bussini, Adelaide;
- Cavalli, Silvia;
- Ciccozzi, Massimo;
- Zollo, Massimo
Publication type:
Letter
Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice.
Published in:
Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0281-5
By:
- Götzl, Julia K.;
- Colombo, Alessio-Vittorio;
- Fellerer, Katrin;
- Reifschneider, Anika;
- Werner, Georg;
- Tahirovic, Sabina;
- Haass, Christian;
- Capell, Anja
Publication type:
Article
Dual Cleavage of Neuregulin 1 Type III by BACE1 and ADAM 17 Liberates Its EGF-Like Domain and Allows Paracrine Signaling.
Published in:
Journal of Neuroscience, 2013, v. 33, n. 18, p. 7856, doi. 10.1523/JNEUROSCI.3372-12.2013
By:
- Fleck, Daniel;
- van Bebber, Frauke;
- Colombo, Alessio;
- Galante, Chiara;
- Schwenk, Benjamin M.;
- Rabe, Linnea;
- Hampel, Heike;
- Novak, Bozidar;
- Kremmer, Elisabeth;
- Tahirovic, Sabina;
- Edbauer, Dieter;
- Lichtenthaler, Stefan F.;
- Schmid, Bettina;
- Willem, Michael;
- Haass, Christian
Publication type:
Article
Loss of PAFAH1B2 Reduces Amyloid-β Generation by Promoting the Degradation of Amyloid Precursor Protein C-Terminal Fragments.
Published in:
Journal of Neuroscience, 2012, v. 32, n. 50, p. 18204, doi. 10.1523/JNEUROSCI.2681-12.2012
By:
- Page, Richard M.;
- Münch, Anna;
- Horn, Thomas;
- Kuhn, Peer-Hendrik;
- Colombo, Alessio;
- Reiner, Orly;
- Boutros, Michael;
- Steiner, Harald;
- Lichtenthaler, Stefan F.;
- Haass, Christian
Publication type:
Article
Adenine phosphoribosyltransferase (APRT) deficiency: identification of a novel nonsense mutation.
Published in:
BMC Nephrology, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2369-15-102
By:
- Valaperta, Rea;
- Rizzo, Vittoria;
- Lombardi, Fortunata;
- Verdelli, Chiara;
- Piccoli, Marco;
- Ghiroldi, Andrea;
- Creo, Pasquale;
- Colombo, Alessio;
- Valisi, Massimiliano;
- Margiotta, Elisabetta;
- Panella, Rossella;
- Costa, Elena
Publication type:
Article
Adenine phosphoribosyltransferase (APRT) deficiency: identification of a novel nonsense mutation.
Published in:
2014
By:
- Valaperta, Rea;
- Rizzo, Vittoria;
- Lombardi, Fortunata;
- Verdelli, Chiara;
- Piccoli, Marco;
- Ghiroldi, Andrea;
- Creo, Pasquale;
- Colombo, Alessio;
- Valisi, Massimiliano;
- Margiotta, Elisabetta;
- Panella, Rossella;
- Costa, Elena
Publication type:
journal article

Found: 39