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- Title
ERICA: cardiovascular risks associated with oral contraceptive use among Brazilian adolescents.
- Authors
de Siqueira Barros, Bruna; Kuschnir, Maria Cristina Caetano; Kuschnir, Fábio Chigres; de Oliveira Costa Jordão, Érica Azevedo
- Abstract
Objective: To investigate the association between oral contraceptive use and cardiovascular risks, including metabolic syndrome and their components in Brazilian adolescents. Method: This study used data from the Study of Cardiovascular Risks in Adolescents (Estudo de Riscos Cardiovasculares em Adolescentes - ERICA), a nationwide, cross-sectional, school-based study with individuals aged 12-17 years. Sociodemographic variables and OC use were assessed by a self-administered questionnaire. International Diabetes Federation criteria were used to define metabolic syndrome. Descriptive statistics were reported as prevalence and their respective confidence interval of 95% of oral contraceptives according to variables. Logistic regression was performed. Crude and adjusted odds ratios were calculated. Results: This subsample was composed of 22,682 female adolescents, of which 12.65% reported using oral contraceptives and their use was associated with hypertension and hypertriglyceridemia. These associations remained statistically significant after adjusting for age, school region, race, and tobacco use with an increase of 2.68 (1.66 - 4.32) and 3.45 (2.56 - 4.65) times, respectively. Conclusion: The present study was the first to examine the association between the use of oral contraceptives and cardiovascular risk factors among the largest number of female Brazilian adolescents. This method was significantly associated with hypertension, hypertriglyceridemia. Teenagers using oral contraceptives should be monitored for side effects, including blood pressure measurements and advised to avoid smoking.
- Subjects
SIDE effects of oral contraceptives; HEART disease risk factors; ADOLESCENT health; METABOLIC syndrome; HYPERTENSION; HYPERTRIGLYCERIDEMIA
- Publication
Jornal de Pediatria, 2022, Vol 98, Issue 1, p53
- ISSN
0021-7557
- Publication type
Article
- DOI
10.1016/j.jped.2021.03.006