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- Title
Significance of microbleeds in patients with transient ischaemic attack.
- Authors
Fluri, F.; Jax, F.; Amort, M.; Wetzel, S. G.; Lyrer, P. A.; Katan, M.; Hatz, F.; Engelter, S. T.
- Abstract
Background and purpose: The aim of this study was to determine the prognostic significance of microbleeds in TIA-patients. In patients with a transient ischaemic attack (TIA), the prognostic value of microbleeds is unknown. Methods: In 176 consecutive TIA patients, the number, size, and location of microbleeds with or without acute ischaemic lesions were assessed. We compared microbleed-positive and microbleed-negative patients with regard to the end-point stroke within 3 months. Results: Four of the seven patients with subsequent stroke had microbleeds. Microbleed-positive patients had a higher risk for stroke [odds ratios (OR) 8.91, 95% CI 1.87-42.51, P < 0.01] than those without microbleeds. Microbleed-positive patients with accompanying acute ischaemic lesions had a higher stroke risk than those with neither an acute ischaemia nor a microbleed (OR 6.20, 95% CI 1.10-35.12; P = 0.04). Conclusion: Microbleeds alone or in combination with acute ischaemic lesions may increase the risk for subsequent ischaemic stroke after TIA within 3 months.
- Subjects
ISCHEMIA; CEREBRAL ischemia; CEREBROVASCULAR disease; BLOOD circulation disorders; BLOOD hyperviscosity syndrome
- Publication
European Journal of Neurology, 2012, Vol 19, Issue 3, p522
- ISSN
1351-5101
- Publication type
Article
- DOI
10.1111/j.1468-1331.2011.03522.x