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- Title
An efficient synthesis of novel dihydrothiazol-2-yl-amides via cyclisation of propargylic carbamothioyl-amides.
- Authors
Saeedi, Mina; Goli, Fereshteh; Mahdavi, Mohammad; Sarihi, Pouria; Asadipour, Ali; Shafiee, Abbas; Foroumadi, Alireza
- Abstract
An efficient protocol is described for the versatile synthesis of novel dihydrothiazol-2-yl-amide derivatives via the regioselective 5-exo-dig heterocyclisation of N-propargyl carbamothioyl-amides in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) in refluxing ethanol. All products were obtained in good yields and short reaction time (10-30 min).
- Subjects
AMIDES; ORGANIC compounds; CHEMICAL synthesis; CLICK chemistry; CYCLIC compounds
- Publication
Journal of Chemical Research, 2014, Vol 38, Issue 3, p131
- ISSN
1747-5198
- Publication type
Article
- DOI
10.3184/174751914X13899480812215