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- Title
False-negative 18F-PSMA-1007 PET/CT in metastatic prostate cancer related to high physiologic liver uptake.
- Authors
Hartrampf, Philipp E.; Seitz, Anna Katharina; Krebs, Markus; Buck, Andreas K.; Lapa, Constantin
- Abstract
This article is part of the Topical Collection on Oncology - Genitourinary A 71-year-old man with advanced castration-resistant prostate cancer was referred to our department for evaluation of prostate-specific membrane antigen (PSMA)-directed radioligand therapy (RLT). In order to rule out PSMA-negative disease, SP 18 sp F-FDG-PET CT (Figure c) was additionally performed [[1]], demonstrating two FDG-avid liver lesions highly suspicious for hepatic metastases without corresponding SP 18 sp F-PSMA-1007 uptake (Figure c red arrows; axial slices: Figure e and f).
- Subjects
METASTASIS; PROSTATE cancer; POSITRON emission tomography computed tomography; CASTRATION-resistant prostate cancer; EXOCRINE glands
- Publication
European Journal of Nuclear Medicine & Molecular Imaging, 2020, Vol 47, Issue 8, p2044
- ISSN
1619-7070
- Publication type
Article
- DOI
10.1007/s00259-019-04645-5