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- Title
Epidemiology of Rotavirus Infection in Children from a Rural and Urban Area, in Maputo, Southern Mozambique, before Vaccine Introduction.
- Authors
De Deus, Nilsa; João, Eva; Cuamba, Assa; Cassocera, Marta; Luıs, Leopoldina; Acácio, Sozinho; Mandomando, Inácio; Augusto, Orvalho; Page, Nicola; Luís, Leopoldina; Deus, Nilsa de
- Abstract
This study aimed to describe the epidemiology of rotavirus infections in Mozambique before vaccine introduction. Between February 2012 and September 2013, stool specimens, demographic and clinical data were collected from 384 children <5 years old hospitalized with acute diarrhea in Mavalane General Hospital and Manhiça District Hospital, southern Mozambique. The samples were tested for rotavirus A using enzyme-linked immunosorbent assay. The overall prevalence of rotavirus infection was 42.4% [95% confidence interval (95CI): 37.4-47.6%], and was similar in Manhiça (44.3%; 95CI: 36.2-52.7%) and Mavalane (41.3%; 95CI: 34.9-47.9%). The highest prevalence of rotavirus infection was observed in children between 6 and 11 months old. It was also observed that 162 (43.7%) of the children were underweight (weight-for-age z-score < -2), of which 61 were infected by rotavirus.
- Subjects
MOZAMBIQUE; ROTAVIRUS vaccines; VIRAL diseases in children; FECAL analysis; DIAGNOSTIC specimens; COMPARATIVE studies; DIARRHEA; ENZYME-linked immunosorbent assay; FECES; GASTROENTERITIS; HOSPITAL care; RESEARCH methodology; MEDICAL cooperation; RESEARCH; RETROVIRUS diseases; RURAL population; ROTAVIRUSES; EVALUATION research; DISEASE prevalence; CROSS-sectional method
- Publication
Journal of Tropical Pediatrics, 2018, Vol 64, Issue 2, p141
- ISSN
0142-6338
- Publication type
journal article
- DOI
10.1093/tropej/fmx032