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- Title
Altered Serum Levels of Sex Steroids and Biotransformation Enzyme Activities by Long-term Alachlor Exposure in Crucian Carp ( Carassius auratus).
- Authors
Yi, X.; Liu, H.; Lu, Y.; Tao, J.; Ding, H.; Zhang, M.; Jiang, W.
- Abstract
This article discusses the effects of the herbicide alachlor on the reproductive health of crucian carp in China. According to the authors, alachlor is an endocrine disrupting chemical which may disrupt growth, development and reproduction in animals and humans. They measured the serum levels of sex hormones ( testerone and estradiol) and activities of hepatic microsome enzymes (glutathione 5-transferase (GST) and UDP-glucuronosyltransferase (UDPGT). They found that alachlor exposure significantly decreased serum testosterone levels and GST activities were continuously inducedwith a marked inhibition to UDPGT activity at all doses. They concluded that alachlor may have profound effects on the reproductive success of this fish species and other fish.
- Subjects
CHINA; ALACHLOR; HERBICIDES; ENDOCRINE disruptors; CRUCIAN carp; ENZYMES; SERUM; TESTOSTERONE; GLUTATHIONE; GLUCURONOSYLTRANSFERASE
- Publication
Bulletin of Environmental Contamination & Toxicology, 2007, Vol 79, Issue 3, p283
- ISSN
0007-4861
- Publication type
Article
- DOI
10.1007/s00128-007-9245-0